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Glyoxylate detoxification is an essential function of malate synthase required for carbon assimilation in Mycobacterium tuberculosis.
Puckett S, Trujillo C, Wang Z, Eoh H, Ioerger TR, Krieger I, Sacchettini J, Schnappinger D, Rhee KY, Ehrt S. Puckett S, et al. Among authors: trujillo c. Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):E2225-E2232. doi: 10.1073/pnas.1617655114. Epub 2017 Mar 6. Proc Natl Acad Sci U S A. 2017. PMID: 28265055 Free PMC article.
Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy.
Koh EI, Oluoch PO, Ruecker N, Proulx MK, Soni V, Murphy KC, Papavinasasundaram K, Reames CJ, Trujillo C, Zaveri A, Zimmerman MD, Aslebagh R, Baker RE, Shaffer SA, Guinn KM, Fitzgerald M, Dartois V, Ehrt S, Hung DT, Ioerger TR, Rubin EJ, Rhee KY, Schnappinger D, Sassetti CM. Koh EI, et al. Among authors: trujillo c. Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2201632119. doi: 10.1073/pnas.2201632119. Epub 2022 Apr 5. Proc Natl Acad Sci U S A. 2022. PMID: 35380903 Free PMC article.
374 results