de Winter W - Search Results

1

The variability in beta-cell function in placebo-treated subjects with type 2 diabetes: application of the weight-HbA1c-insulin-glucose (WHIG) model.

Duong JK, de Winter W, Choy S, Plock N, Naik H, Krauwinkel W, Visser SA, Verhamme KM, Sturkenboom MC, Stricker BH, Danhof M. Duong JK, et al. Among authors: de winter w. Br J Clin Pharmacol. 2017 Mar;83(3):487-497. doi: 10.1111/bcp.13144. Epub 2016 Nov 17. Br J Clin Pharmacol. 2017. PMID: 27679422 Free PMC article.

2

Weight-HbA1c-insulin-glucose model for describing disease progression of type 2 diabetes.

Choy S, Kjellsson MC, Karlsson MO, de Winter W. Choy S, et al. Among authors: de winter w. CPT Pharmacometrics Syst Pharmacol. 2016 Jan;5(1):11-9. doi: 10.1002/psp4.12051. Epub 2015 Dec 16. CPT Pharmacometrics Syst Pharmacol. 2016. PMID: 26844011 Free PMC article. Clinical Trial.

3

Modeling the Disease Progression from Healthy to Overt Diabetes in ZDSD Rats.

Choy S, de Winter W, Karlsson MO, Kjellsson MC. Choy S, et al. Among authors: de winter w. AAPS J. 2016 Sep;18(5):1203-1212. doi: 10.1208/s12248-016-9931-0. Epub 2016 May 31. AAPS J. 2016. PMID: 27245226

4

A mechanism-based disease progression model for comparison of long-term effects of pioglitazone, metformin and gliclazide on disease processes underlying Type 2 Diabetes Mellitus.

de Winter W, DeJongh J, Post T, Ploeger B, Urquhart R, Moules I, Eckland D, Danhof M. de Winter W, et al. J Pharmacokinet Pharmacodyn. 2006 Jun;33(3):313-43. doi: 10.1007/s10928-006-9008-2. Epub 2006 Mar 22. J Pharmacokinet Pharmacodyn. 2006. PMID: 16552630

5

Dynamic population pharmacokinetic-pharmacodynamic modelling and simulation supports similar efficacy in glycosylated haemoglobin response with once or twice-daily dosing of canagliflozin.

de Winter W, Dunne A, de Trixhe XW, Devineni D, Hsu CH, Pinheiro J, Polidori D. de Winter W, et al. Br J Clin Pharmacol. 2017 May;83(5):1072-1081. doi: 10.1111/bcp.13180. Epub 2017 Jan 31. Br J Clin Pharmacol. 2017. PMID: 28138980 Free PMC article. Clinical Trial.

6

Population Pharmacokinetic Modeling of Canagliflozin in Healthy Volunteers and Patients with Type 2 Diabetes Mellitus.

Hoeben E, De Winter W, Neyens M, Devineni D, Vermeulen A, Dunne A. Hoeben E, et al. Among authors: de winter w. Clin Pharmacokinet. 2016 Feb;55(2):209-23. doi: 10.1007/s40262-015-0307-x. Clin Pharmacokinet. 2016. PMID: 26293616 Clinical Trial.

7

Characterization of the ZDSD Rat: A Translational Model for the Study of Metabolic Syndrome and Type 2 Diabetes.

Peterson RG, Jackson CV, Zimmerman K, de Winter W, Huebert N, Hansen MK. Peterson RG, et al. Among authors: de winter w. J Diabetes Res. 2015;2015:487816. doi: 10.1155/2015/487816. Epub 2015 Apr 16. J Diabetes Res. 2015. PMID: 25961053 Free PMC article.

8

The method of averaging applied to pharmacokinetic/pharmacodynamic indirect response models.

Dunne A, de Winter W, Hsu CH, Mariam S, Neyens M, Pinheiro J, Woot de Trixhe X. Dunne A, et al. Among authors: de winter w. J Pharmacokinet Pharmacodyn. 2015 Aug;42(4):417-26. doi: 10.1007/s10928-015-9426-0. Epub 2015 Jul 5. J Pharmacokinet Pharmacodyn. 2015. PMID: 26142076

9

Impact of saturable distribution in compartmental PK models: dynamics and practical use.

Peletier LA, de Winter W. Peletier LA, et al. Among authors: de winter w. J Pharmacokinet Pharmacodyn. 2017 Feb;44(1):1-16. doi: 10.1007/s10928-016-9500-2. Epub 2017 Jan 3. J Pharmacokinet Pharmacodyn. 2017. PMID: 28050672 Free PMC article.

10

Profiling the subjective effects of Δ⁹-tetrahydrocannabinol using visual analogue scales.

Kleinloog D, Roozen F, De Winter W, Freijer J, Van Gerven J. Kleinloog D, et al. Among authors: de winter w. Int J Methods Psychiatr Res. 2014 Jun;23(2):245-56. doi: 10.1002/mpr.1424. Epub 2014 Feb 5. Int J Methods Psychiatr Res. 2014. PMID: 24496889 Free PMC article.

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