Ye JQ - Search Results

1

Design and discovery of 4-anilinoquinazoline-urea derivatives as dual TK inhibitors of EGFR and VEGFR-2.

Zhang HQ, Gong FH, Ye JQ, Zhang C, Yue XH, Li CG, Xu YG, Sun LP. Zhang HQ, et al. Among authors: ye jq. Eur J Med Chem. 2017 Jan 5;125:245-254. doi: 10.1016/j.ejmech.2016.09.039. Epub 2016 Sep 14. Eur J Med Chem. 2017. PMID: 27688180

2

Novel N-Substituted oseltamivir derivatives as potent influenza neuraminidase inhibitors: Design, synthesis, biological evaluation, ADME prediction and molecular docking studies.

Ye J, Yang X, Xu M, Chan PK, Ma C. Ye J, et al. Eur J Med Chem. 2019 Nov 15;182:111635. doi: 10.1016/j.ejmech.2019.111635. Epub 2019 Aug 22. Eur J Med Chem. 2019. PMID: 31493744

3

Discovery of Antibacterials That Inhibit Bacterial RNA Polymerase Interactions with Sigma Factors.

Ye J, Chu AJ, Harper R, Chan ST, Shek TL, Zhang Y, Ip M, Sambir M, Artsimovitch I, Zuo Z, Yang X, Ma C. Ye J, et al. J Med Chem. 2020 Jul 23;63(14):7695-7720. doi: 10.1021/acs.jmedchem.0c00520. Epub 2020 Jul 7. J Med Chem. 2020. PMID: 32633513 Free PMC article.

4

Discovery of a potent tyrosine kinase AXL inhibitor bearing the 3-((2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)amino)pyrazine core.

Wang Y, Xing L, Ji Y, Ye J, Dai Y, Gu W, Ai J, Song Z. Wang Y, et al. Bioorg Med Chem Lett. 2019 Mar 15;29(6):836-838. doi: 10.1016/j.bmcl.2019.01.018. Epub 2019 Jan 21. Bioorg Med Chem Lett. 2019. PMID: 30685094

5

Benzyl and benzoyl benzoic acid inhibitors of bacterial RNA polymerase-sigma factor interaction.

Ye J, Chu AJ, Lin L, Chan ST, Harper R, Xiao M, Artsimovitch I, Zuo Z, Ma C, Yang X. Ye J, et al. Eur J Med Chem. 2020 Dec 15;208:112671. doi: 10.1016/j.ejmech.2020.112671. Epub 2020 Aug 18. Eur J Med Chem. 2020. PMID: 32920341 Free PMC article.

6

Design, Synthesis, Biological Evaluation and In Silico Studies of Pyrazole-Based NH₂-Acyl Oseltamivir Analogues as Potent Neuraminidase Inhibitors.

Ye J, Lin L, Xu J, Chan PK, Yang X, Ma C. Ye J, et al. Pharmaceuticals (Basel). 2021 Apr 16;14(4):371. doi: 10.3390/ph14040371. Pharmaceuticals (Basel). 2021. PMID: 33923858 Free PMC article.

7

Anti-inflammatory effect of the six compounds isolated from Nauclea officinalis Pierrc ex Pitard, and molecular mechanism of strictosamide via suppressing the NF-κB and MAPK signaling pathway in LPS-induced RAW 264.7 macrophages.

Li D, Chen J, Ye J, Zhai X, Song J, Jiang C, Wang J, Zhang H, Jia X, Zhu F. Li D, et al. J Ethnopharmacol. 2017 Jan 20;196:66-74. doi: 10.1016/j.jep.2016.12.007. Epub 2016 Dec 15. J Ethnopharmacol. 2017. PMID: 27989509

8

Nauclea officinalis inhibits inflammation in LPS-mediated RAW 264.7 macrophages by suppressing the NF-κB signaling pathway.

Zhai XT, Zhang ZY, Jiang CH, Chen JQ, Ye JQ, Jia XB, Yang Y, Ni Q, Wang SX, Song J, Zhu FX. Zhai XT, et al. Among authors: ye jq. J Ethnopharmacol. 2016 May 13;183:159-165. doi: 10.1016/j.jep.2016.01.018. Epub 2016 Jan 19. J Ethnopharmacol. 2016. PMID: 26806575

9

Sulfonamidyl derivatives of sigmacidin: Protein-protein interaction inhibitors targeting bacterial RNA polymerase and sigma factor interaction exhibiting antimicrobial activity against antibiotic-resistant bacteria.

Ye J, Kan CH, Zheng Y, Tsang TF, Chu AJ, Chan KH, Yang X, Ma C. Ye J, et al. Bioorg Chem. 2024 Feb;143:106983. doi: 10.1016/j.bioorg.2023.106983. Epub 2023 Nov 23. Bioorg Chem. 2024. PMID: 38016396

10

QSAR, Docking, and Molecular Dynamics Simulation Studies of Sigmacidins as Antimicrobials against Streptococci.

Ye J, Yang X, Ma C. Ye J, et al. Int J Mol Sci. 2022 Apr 7;23(8):4085. doi: 10.3390/ijms23084085. Int J Mol Sci. 2022. PMID: 35456906 Free PMC article.

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