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Expression of TGF-β Signaling Regulator RBPMS (RNA-Binding Protein With Multiple Splicing) Is Regulated by IL-1β and TGF-β Superfamily Members, and Decreased in Aged and Osteoarthritic Cartilage.
Shanmugaapriya S, van Caam A, de Kroon L, Vitters EL, Walgreen B, van Beuningen H, Davidson EB, van der Kraan PM. Shanmugaapriya S, et al. Among authors: van beuningen h, van der kraan pm, van caam a. Cartilage. 2016 Oct;7(4):333-45. doi: 10.1177/1947603515623991. Epub 2016 Feb 24. Cartilage. 2016. PMID: 27688842 Free PMC article.
TGF-β dampens IL-6 signaling in articular chondrocytes by decreasing IL-6 receptor expression.
Wiegertjes R, van Caam A, van Beuningen H, Koenders M, van Lent P, van der Kraan P, van de Loo F, Blaney Davidson E. Wiegertjes R, et al. Among authors: van beuningen h, van de loo f, van lent p, van caam a, van der kraan p. Osteoarthritis Cartilage. 2019 Aug;27(8):1197-1207. doi: 10.1016/j.joca.2019.04.014. Epub 2019 May 2. Osteoarthritis Cartilage. 2019. PMID: 31054955 Free article.
The high affinity ALK1-ligand BMP9 induces a hypertrophy-like state in chondrocytes that is antagonized by TGFβ1.
van Caam A, Blaney Davidson E, Garcia de Vinuesa A, van Geffen E, van den Berg W, Goumans MJ, ten Dijke P, van der Kraan P. van Caam A, et al. Among authors: van geffen e, van den berg w, van der kraan p. Osteoarthritis Cartilage. 2015 Jun;23(6):985-95. doi: 10.1016/j.joca.2015.02.007. Epub 2015 Feb 12. Osteoarthritis Cartilage. 2015. PMID: 25681563 Free article.
Expression of TGFβ-family signalling components in ageing cartilage: age-related loss of TGFβ and BMP receptors.
van Caam A, Madej W, Thijssen E, Garcia de Vinuesa A, van den Berg W, Goumans MJ, Ten Dijke P, Blaney Davidson E, van der Kraan PM. van Caam A, et al. Among authors: van der kraan pm, van den berg w. Osteoarthritis Cartilage. 2016 Jul;24(7):1235-45. doi: 10.1016/j.joca.2016.02.008. Epub 2016 Mar 12. Osteoarthritis Cartilage. 2016. PMID: 26975812 Free article.
Patient involvement in basic rheumatology research at Nijmegen: a three year's responsive evaluation of added value, pitfalls and conditions for success.
de Wit MPT, Koenders MI, Neijland Y, van den Hoogen FHJ, van der Kraan PM, van de Loo FAJ, Berkers H, Lieon M, van Caam A, van den Ende C. de Wit MPT, et al. Among authors: van caam a. BMC Rheumatol. 2022 Oct 7;6(1):66. doi: 10.1186/s41927-022-00296-6. BMC Rheumatol. 2022. PMID: 36203190 Free PMC article.
Cell-integrated serum-induced signalling patterns can differentiate between hand and knee osteoarthritis patients.
Neefjes M, Housmans BAC, Kaffa C, Thielen NGM, Joosten LAB, van den Ende CHM, Vitters EL, van den Akker GGH, Welting TJM, van Caam APM, van der Kraan PM. Neefjes M, et al. Among authors: van caam apm. Rheumatology (Oxford). 2024 Nov 18:keae555. doi: 10.1093/rheumatology/keae555. Online ahead of print. Rheumatology (Oxford). 2024. PMID: 39558621
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