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Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease.
Chan EY, Luthi-Carter R, Strand A, Solano SM, Hanson SA, DeJohn MM, Kooperberg C, Chase KO, DiFiglia M, Young AB, Leavitt BR, Cha JH, Aronin N, Hayden MR, Olson JM. Chan EY, et al. Among authors: difiglia m. Hum Mol Genet. 2002 Aug 15;11(17):1939-51. doi: 10.1093/hmg/11.17.1939. Hum Mol Genet. 2002. PMID: 12165556
Huntingtin associates with acidic phospholipids at the plasma membrane.
Kegel KB, Sapp E, Yoder J, Cuiffo B, Sobin L, Kim YJ, Qin ZH, Hayden MR, Aronin N, Scott DL, Isenberg G, Goldmann WH, DiFiglia M. Kegel KB, et al. Among authors: difiglia m. J Biol Chem. 2005 Oct 28;280(43):36464-73. doi: 10.1074/jbc.M503672200. Epub 2005 Aug 5. J Biol Chem. 2005. PMID: 16085648 Free article.
A function of huntingtin in guanine nucleotide exchange on Rab11.
Li X, Sapp E, Valencia A, Kegel KB, Qin ZH, Alexander J, Masso N, Reeves P, Ritch JJ, Zeitlin S, Aronin N, Difiglia M. Li X, et al. Among authors: difiglia m. Neuroreport. 2008 Oct 29;19(16):1643-7. doi: 10.1097/WNR.0b013e328315cd4c. Neuroreport. 2008. PMID: 18845944
193 results