Vander Heiden JA - Search Results

1

A Model of Somatic Hypermutation Targeting in Mice Based on High-Throughput Ig Sequencing Data.

Cui A, Di Niro R, Vander Heiden JA, Briggs AW, Adams K, Gilbert T, O'Connor KC, Vigneault F, Shlomchik MJ, Kleinstein SH. Cui A, et al. Among authors: vander heiden ja. J Immunol. 2016 Nov 1;197(9):3566-3574. doi: 10.4049/jimmunol.1502263. Epub 2016 Oct 5. J Immunol. 2016. PMID: 27707999 Free PMC article.

2

Models of somatic hypermutation targeting and substitution based on synonymous mutations from high-throughput immunoglobulin sequencing data.

Yaari G, Vander Heiden JA, Uduman M, Gadala-Maria D, Gupta N, Stern JN, O'Connor KC, Hafler DA, Laserson U, Vigneault F, Kleinstein SH. Yaari G, et al. Among authors: vander heiden ja. Front Immunol. 2013 Nov 15;4:358. doi: 10.3389/fimmu.2013.00358. eCollection 2013. Front Immunol. 2013. PMID: 24298272 Free PMC article.

3

pRESTO: a toolkit for processing high-throughput sequencing raw reads of lymphocyte receptor repertoires.

Vander Heiden JA, Yaari G, Uduman M, Stern JN, O'Connor KC, Hafler DA, Vigneault F, Kleinstein SH. Vander Heiden JA, et al. Bioinformatics. 2014 Jul 1;30(13):1930-2. doi: 10.1093/bioinformatics/btu138. Epub 2014 Mar 10. Bioinformatics. 2014. PMID: 24618469 Free PMC article.

4

Salmonella Infection Drives Promiscuous B Cell Activation Followed by Extrafollicular Affinity Maturation.

Di Niro R, Lee SJ, Vander Heiden JA, Elsner RA, Trivedi N, Bannock JM, Gupta NT, Kleinstein SH, Vigneault F, Gilbert TJ, Meffre E, McSorley SJ, Shlomchik MJ. Di Niro R, et al. Among authors: vander heiden ja. Immunity. 2015 Jul 21;43(1):120-31. doi: 10.1016/j.immuni.2015.06.013. Epub 2015 Jul 14. Immunity. 2015. PMID: 26187411 Free PMC article.

5

Dysregulation of B Cell Repertoire Formation in Myasthenia Gravis Patients Revealed through Deep Sequencing.

Vander Heiden JA, Stathopoulos P, Zhou JQ, Chen L, Gilbert TJ, Bolen CR, Barohn RJ, Dimachkie MM, Ciafaloni E, Broering TJ, Vigneault F, Nowak RJ, Kleinstein SH, O'Connor KC. Vander Heiden JA, et al. J Immunol. 2017 Feb 15;198(4):1460-1473. doi: 10.4049/jimmunol.1601415. Epub 2017 Jan 13. J Immunol. 2017. PMID: 28087666 Free PMC article.

6

Influence of seasonal exposure to grass pollen on local and peripheral blood IgE repertoires in patients with allergic rhinitis.

Wu YC, James LK, Vander Heiden JA, Uduman M, Durham SR, Kleinstein SH, Kipling D, Gould HJ. Wu YC, et al. Among authors: vander heiden ja. J Allergy Clin Immunol. 2014 Sep;134(3):604-12. doi: 10.1016/j.jaci.2014.07.010. J Allergy Clin Immunol. 2014. PMID: 25171866 Free PMC article.

7

Change-O: a toolkit for analyzing large-scale B cell immunoglobulin repertoire sequencing data.

Gupta NT, Vander Heiden JA, Uduman M, Gadala-Maria D, Yaari G, Kleinstein SH. Gupta NT, et al. Among authors: vander heiden ja. Bioinformatics. 2015 Oct 15;31(20):3356-8. doi: 10.1093/bioinformatics/btv359. Epub 2015 Jun 10. Bioinformatics. 2015. PMID: 26069265 Free PMC article.

8

The mutation patterns in B-cell immunoglobulin receptors reflect the influence of selection acting at multiple time-scales.

Yaari G, Benichou JI, Vander Heiden JA, Kleinstein SH, Louzoun Y. Yaari G, et al. Among authors: vander heiden ja. Philos Trans R Soc Lond B Biol Sci. 2015 Sep 5;370(1676):20140242. doi: 10.1098/rstb.2014.0242. Philos Trans R Soc Lond B Biol Sci. 2015. PMID: 26194756 Free PMC article.

9

Interleukin-10 from CD4⁺ follicular regulatory T cells promotes the germinal center response.

Laidlaw BJ, Lu Y, Amezquita RA, Weinstein JS, Vander Heiden JA, Gupta NT, Kleinstein SH, Kaech SM, Craft J. Laidlaw BJ, et al. Among authors: vander heiden ja. Sci Immunol. 2017 Oct 20;2(16):eaan4767. doi: 10.1126/sciimmunol.aan4767. Sci Immunol. 2017. PMID: 29054998 Free PMC article.

10

Repertoire-wide phylogenetic models of B cell molecular evolution reveal evolutionary signatures of aging and vaccination.

Hoehn KB, Vander Heiden JA, Zhou JQ, Lunter G, Pybus OG, Kleinstein SH. Hoehn KB, et al. Among authors: vander heiden ja. Proc Natl Acad Sci U S A. 2019 Nov 5;116(45):22664-22672. doi: 10.1073/pnas.1906020116. Epub 2019 Oct 21. Proc Natl Acad Sci U S A. 2019. PMID: 31636219 Free PMC article.

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