Grove NC - Search Results

1

Homology Requirements for Efficient, Footprintless Gene Editing at the CFTR Locus in Human iPSCs with Helper-dependent Adenoviral Vectors.

Palmer DJ, Grove NC, Ing J, Crane AM, Venken K, Davis BR, Ng P. Palmer DJ, et al. Among authors: grove nc. Mol Ther Nucleic Acids. 2016 Oct 11;5(10):e372. doi: 10.1038/mtna.2016.83. Mol Ther Nucleic Acids. 2016. PMID: 27727248 Free PMC article.

2

Helper virus-mediated downregulation of transgene expression permits production of recalcitrant helper-dependent adenoviral vector.

Palmer DJ, Grove NC, Ng P. Palmer DJ, et al. Among authors: grove nc. Mol Ther Methods Clin Dev. 2016 Jun 8;3:16039. doi: 10.1038/mtm.2016.39. eCollection 2016. Mol Ther Methods Clin Dev. 2016. PMID: 27331077 Free PMC article.

3

Gene Editing with Helper-Dependent Adenovirus Can Efficiently Introduce Multiple Changes Simultaneously over a Large Genomic Region.

Palmer DJ, Grove NC, Turner DL, Ng P. Palmer DJ, et al. Among authors: grove nc. Mol Ther Nucleic Acids. 2017 Sep 15;8:101-110. doi: 10.1016/j.omtn.2017.06.001. Epub 2017 Jun 7. Mol Ther Nucleic Acids. 2017. PMID: 28918012 Free PMC article.

4

Balloon catheter delivery of helper-dependent adenoviral vector results in sustained, therapeutic hFIX expression in rhesus macaques.

Brunetti-Pierri N, Liou A, Patel P, Palmer D, Grove N, Finegold M, Piccolo P, Donnachie E, Rice K, Beaudet A, Mullins C, Ng P. Brunetti-Pierri N, et al. Mol Ther. 2012 Oct;20(10):1863-70. doi: 10.1038/mt.2012.143. Epub 2012 Jul 24. Mol Ther. 2012. PMID: 22828499 Free PMC article.

5

Transgene expression up to 7 years in nonhuman primates following hepatic transduction with helper-dependent adenoviral vectors.

Brunetti-Pierri N, Ng T, Iannitti D, Cioffi W, Stapleton G, Law M, Breinholt J, Palmer D, Grove N, Rice K, Bauer C, Finegold M, Beaudet A, Mullins C, Ng P. Brunetti-Pierri N, et al. Hum Gene Ther. 2013 Aug;24(8):761-5. doi: 10.1089/hum.2013.071. Hum Gene Ther. 2013. PMID: 23902403 Free PMC article.

6

Efficient, long-term hepatic gene transfer using clinically relevant HDAd doses by balloon occlusion catheter delivery in nonhuman primates.

Brunetti-Pierri N, Stapleton GE, Law M, Breinholt J, Palmer DJ, Zuo Y, Grove NC, Finegold MJ, Rice K, Beaudet AL, Mullins CE, Ng P. Brunetti-Pierri N, et al. Among authors: grove nc. Mol Ther. 2009 Feb;17(2):327-33. doi: 10.1038/mt.2008.257. Epub 2008 Dec 2. Mol Ther. 2009. PMID: 19050700 Free PMC article.

7

Bioengineered factor IX molecules with increased catalytic activity improve the therapeutic index of gene therapy vectors for hemophilia B.

Brunetti-Pierri N, Grove NC, Zuo Y, Edwards R, Palmer D, Cerullo V, Teruya J, Ng P. Brunetti-Pierri N, et al. Among authors: grove nc. Hum Gene Ther. 2009 May;20(5):479-85. doi: 10.1089/hum.2008.084. Hum Gene Ther. 2009. PMID: 19196177 Free PMC article.

8

Vasoactive intestinal peptide increases hepatic transduction and reduces innate immune response following administration of helper-dependent Ad.

Vetrini F, Brunetti-Pierri N, Palmer DJ, Bertin T, Grove NC, Finegold MJ, Ng P. Vetrini F, et al. Among authors: grove nc. Mol Ther. 2010 Jul;18(7):1339-45. doi: 10.1038/mt.2010.84. Epub 2010 May 11. Mol Ther. 2010. PMID: 20461064 Free PMC article.

9

SR-A and SREC-I are Kupffer and endothelial cell receptors for helper-dependent adenoviral vectors.

Piccolo P, Vetrini F, Mithbaokar P, Grove NC, Bertin T, Palmer D, Ng P, Brunetti-Pierri N. Piccolo P, et al. Among authors: grove nc. Mol Ther. 2013 Apr;21(4):767-74. doi: 10.1038/mt.2012.287. Epub 2013 Jan 29. Mol Ther. 2013. PMID: 23358188 Free PMC article.

10

Intrathecal injection of helper-dependent adenoviral vectors results in long-term transgene expression in neuroependymal cells and neurons.

Dindot S, Piccolo P, Grove N, Palmer D, Brunetti-Pierri N. Dindot S, et al. Hum Gene Ther. 2011 Jun;22(6):745-51. doi: 10.1089/hum.2010.147. Epub 2011 Mar 18. Hum Gene Ther. 2011. PMID: 21175294 Free PMC article.

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