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Targeting HIF2α in Clear-Cell Renal Cell Carcinoma.
Ricketts CJ, Crooks DR, Linehan WM. Ricketts CJ, et al. Among authors: crooks dr. Cancer Cell. 2016 Oct 10;30(4):515-517. doi: 10.1016/j.ccell.2016.09.016. Cancer Cell. 2016. PMID: 27728802 Free article.
Deletion of iron regulatory protein 1 causes polycythemia and pulmonary hypertension in mice through translational derepression of HIF2α.
Ghosh MC, Zhang DL, Jeong SY, Kovtunovych G, Ollivierre-Wilson H, Noguchi A, Tu T, Senecal T, Robinson G, Crooks DR, Tong WH, Ramaswamy K, Singh A, Graham BB, Tuder RM, Yu ZX, Eckhaus M, Lee J, Springer DA, Rouault TA. Ghosh MC, et al. Among authors: crooks dr. Cell Metab. 2013 Feb 5;17(2):271-81. doi: 10.1016/j.cmet.2012.12.016. Cell Metab. 2013. PMID: 23395173 Free PMC article.
Targeting ABL1-mediated oxidative stress adaptation in fumarate hydratase-deficient cancer.
Sourbier C, Ricketts CJ, Matsumoto S, Crooks DR, Liao PJ, Mannes PZ, Yang Y, Wei MH, Srivastava G, Ghosh S, Chen V, Vocke CD, Merino M, Srinivasan R, Krishna MC, Mitchell JB, Pendergast AM, Rouault TA, Neckers L, Linehan WM. Sourbier C, et al. Among authors: crooks dr. Cancer Cell. 2014 Dec 8;26(6):840-850. doi: 10.1016/j.ccell.2014.10.005. Cancer Cell. 2014. PMID: 25490448 Free PMC article.
SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery.
Saxena N, Maio N, Crooks DR, Ricketts CJ, Yang Y, Wei MH, Fan TW, Lane AN, Sourbier C, Singh A, Killian JK, Meltzer PS, Vocke CD, Rouault TA, Linehan WM. Saxena N, et al. Among authors: crooks dr. J Natl Cancer Inst. 2016 Jan;108(1):djv287. doi: 10.1093/jnci/djv287. J Natl Cancer Inst. 2016. PMID: 26719882 Free PMC article.
SnapShot: Renal Cell Carcinoma.
Ricketts CJ, Crooks DR, Sourbier C, Schmidt LS, Srinivasan R, Linehan WM. Ricketts CJ, et al. Among authors: crooks dr. Cancer Cell. 2016 Apr 11;29(4):610-610.e1. doi: 10.1016/j.ccell.2016.03.021. Cancer Cell. 2016. PMID: 27070709 Free article.
Co-opting a Bioorthogonal Reaction for Oncometabolite Detection.
Zengeya TT, Garlick JM, Kulkarni RA, Miley M, Roberts AM, Yang Y, Crooks DR, Sourbier C, Linehan WM, Meier JL. Zengeya TT, et al. Among authors: crooks dr. J Am Chem Soc. 2016 Dec 14;138(49):15813-15816. doi: 10.1021/jacs.6b09706. Epub 2016 Nov 30. J Am Chem Soc. 2016. PMID: 27960310 Free PMC article.
ONC201 kills breast cancer cells in vitro by targeting mitochondria.
Greer YE, Porat-Shliom N, Nagashima K, Stuelten C, Crooks D, Koparde VN, Gilbert SF, Islam C, Ubaldini A, Ji Y, Gattinoni L, Soheilian F, Wang X, Hafner M, Shetty J, Tran B, Jailwala P, Cam M, Lang M, Voeller D, Reinhold WC, Rajapakse V, Pommier Y, Weigert R, Linehan WM, Lipkowitz S. Greer YE, et al. Oncotarget. 2018 Apr 6;9(26):18454-18479. doi: 10.18632/oncotarget.24862. eCollection 2018 Apr 6. Oncotarget. 2018. PMID: 29719618 Free PMC article.
A chemoproteomic portrait of the oncometabolite fumarate.
Kulkarni RA, Bak DW, Wei D, Bergholtz SE, Briney CA, Shrimp JH, Alpsoy A, Thorpe AL, Bavari AE, Crooks DR, Levy M, Florens L, Washburn MP, Frizzell N, Dykhuizen EC, Weerapana E, Linehan WM, Meier JL. Kulkarni RA, et al. Among authors: crooks dr. Nat Chem Biol. 2019 Apr;15(4):391-400. doi: 10.1038/s41589-018-0217-y. Epub 2019 Feb 4. Nat Chem Biol. 2019. PMID: 30718813 Free PMC article.
51 results