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Peripheral VH4+ plasmablasts demonstrate autoreactive B cell expansion toward brain antigens in early multiple sclerosis patients.
Rivas JR, Ireland SJ, Chkheidze R, Rounds WH, Lim J, Johnson J, Ramirez DM, Ligocki AJ, Chen D, Guzman AA, Woodhall M, Wilson PC, Meffre E, White C 3rd, Greenberg BM, Waters P, Cowell LG, Stowe AM, Monson NL. Rivas JR, et al. Among authors: cowell lg. Acta Neuropathol. 2017 Jan;133(1):43-60. doi: 10.1007/s00401-016-1627-0. Epub 2016 Oct 11. Acta Neuropathol. 2017. PMID: 27730299 Free PMC article.
CSF-Derived CD4+ T-Cell Diversity Is Reduced in Patients With Alzheimer Clinical Syndrome.
Joshi C, Sivaprakasam K, Christley S, Ireland S, Rivas J, Zhang W, Sader D, Logan R, Lambracht-Washington D, Rosenberg R, Cullum M, Hitt B, Li QZ, Barber R, Greenberg B, Cowell L, Zhang R, Stowe A, Huebinger R, Kelley B, Monson N. Joshi C, et al. Neurol Neuroimmunol Neuroinflamm. 2021 Nov 30;9(1):e1106. doi: 10.1212/NXI.0000000000001106. Print 2022 Jan. Neurol Neuroimmunol Neuroinflamm. 2021. PMID: 34848502 Free PMC article.
Memory B cells from a subset of treatment-naïve relapsing-remitting multiple sclerosis patients elicit CD4(+) T-cell proliferation and IFN-γ production in response to myelin basic protein and myelin oligodendrocyte glycoprotein.
Harp CT, Ireland S, Davis LS, Remington G, Cassidy B, Cravens PD, Stuve O, Lovett-Racke AE, Eagar TN, Greenberg BM, Racke MK, Cowell LG, Karandikar NJ, Frohman EM, Monson NL. Harp CT, et al. Among authors: cowell lg. Eur J Immunol. 2010 Oct;40(10):2942-56. doi: 10.1002/eji.201040516. Eur J Immunol. 2010. PMID: 20812237 Free PMC article.
VDJPipe: a pipelined tool for pre-processing immune repertoire sequencing data.
Christley S, Levin MK, Toby IT, Fonner JM, Monson NL, Rounds WH, Rubelt F, Scarborough W, Scheuermann RH, Cowell LG. Christley S, et al. Among authors: cowell lg. BMC Bioinformatics. 2017 Oct 11;18(1):448. doi: 10.1186/s12859-017-1853-z. BMC Bioinformatics. 2017. PMID: 29020925 Free PMC article.
Reconstituting T cell receptor selection in-silico.
Ostmeyer J, Cowell L, Greenberg B, Christley S. Ostmeyer J, et al. Genes Immun. 2021 Jul;22(3):187-193. doi: 10.1038/s41435-021-00141-9. Epub 2021 Jun 14. Genes Immun. 2021. PMID: 34127826
VDJServer: A Cloud-Based Analysis Portal and Data Commons for Immune Repertoire Sequences and Rearrangements.
Christley S, Scarborough W, Salinas E, Rounds WH, Toby IT, Fonner JM, Levin MK, Kim M, Mock SA, Jordan C, Ostmeyer J, Buntzman A, Rubelt F, Davila ML, Monson NL, Scheuermann RH, Cowell LG. Christley S, et al. Among authors: cowell lg. Front Immunol. 2018 May 8;9:976. doi: 10.3389/fimmu.2018.00976. eCollection 2018. Front Immunol. 2018. PMID: 29867956 Free PMC article.
82 results