Huang M - Search Results

1

Autophagy mediates proteolysis of NPM1 and HEXIM1 and sensitivity to BET inhibition in AML cells.

Huang M, Garcia JS, Thomas D, Zhu L, Nguyen LX, Chan SM, Majeti R, Medeiros BC, Mitchell BS. Huang M, et al. Oncotarget. 2016 Nov 15;7(46):74917-74930. doi: 10.18632/oncotarget.12493. Oncotarget. 2016. PMID: 27732946 Free PMC article.

2

Selective Toxicity of Investigational Ixazomib for Human Leukemia Cells Expressing Mutant Cytoplasmic NPM1: Role of Reactive Oxygen Species.

Garcia JS, Huang M, Medeiros BC, Mitchell BS. Garcia JS, et al. Among authors: huang m. Clin Cancer Res. 2016 Apr 15;22(8):1978-88. doi: 10.1158/1078-0432.CCR-15-1440. Epub 2015 Dec 3. Clin Cancer Res. 2016. PMID: 26634271

3

Brd4 regulates the expression of essential autophagy genes and Keap1 in AML cells.

Huang M, Zhu L, Garcia JS, Li MX, Gentles AJ, Mitchell BS. Huang M, et al. Oncotarget. 2018 Feb 7;9(14):11665-11676. doi: 10.18632/oncotarget.24432. eCollection 2018 Feb 20. Oncotarget. 2018. PMID: 29545928 Free PMC article.

4

Role of cysteine 288 in nucleophosmin cytoplasmic mutations: sensitization to toxicity induced by arsenic trioxide and bortezomib.

Huang M, Thomas D, Li MX, Feng W, Chan SM, Majeti R, Mitchell BS. Huang M, et al. Leukemia. 2013 Oct;27(10):1970-80. doi: 10.1038/leu.2013.222. Epub 2013 Jul 23. Leukemia. 2013. PMID: 23877794

5

Guanine nucleotide depletion mediates translocation of nucleolar proteins, including RNA helicase A (DHX-9).

Huang M, Mitchell BS. Huang M, et al. Nucleosides Nucleotides Nucleic Acids. 2008 Jun;27(6):704-11. doi: 10.1080/15257770802145132. Nucleosides Nucleotides Nucleic Acids. 2008. PMID: 18600529

6

Depletion of guanine nucleotides leads to the Mdm2-dependent proteasomal degradation of nucleostemin.

Huang M, Itahana K, Zhang Y, Mitchell BS. Huang M, et al. Cancer Res. 2009 Apr 1;69(7):3004-12. doi: 10.1158/0008-5472.CAN-08-3413. Epub 2009 Mar 24. Cancer Res. 2009. PMID: 19318567 Free PMC article.

7

ASH1L Links Histone H3 Lysine 36 Dimethylation to MLL Leukemia.

Zhu L, Li Q, Wong SH, Huang M, Klein BJ, Shen J, Ikenouye L, Onishi M, Schneidawind D, Buechele C, Hansen L, Duque-Afonso J, Zhu F, Martin GM, Gozani O, Majeti R, Kutateladze TG, Cleary ML. Zhu L, et al. Among authors: huang m. Cancer Discov. 2016 Jul;6(7):770-83. doi: 10.1158/2159-8290.CD-16-0058. Epub 2016 May 6. Cancer Discov. 2016. PMID: 27154821 Free PMC article.

8

Determinants of sensitivity of human T-cell leukemia CCRF-CEM cells to immucillin-H.

Huang M, Wang Y, Gu J, Yang J, Noel K, Mitchell BS, Schramm VL, Graves LM. Huang M, et al. Leuk Res. 2008 Aug;32(8):1268-78. doi: 10.1016/j.leukres.2007.12.015. Epub 2008 Feb 14. Leuk Res. 2008. PMID: 18279955 Free PMC article.

9

Reactive oxygen species regulate nucleostemin oligomerization and protein degradation.

Huang M, Whang P, Chodaparambil JV, Pollyea DA, Kusler B, Xu L, Felsher DW, Mitchell BS. Huang M, et al. J Biol Chem. 2011 Apr 1;286(13):11035-46. doi: 10.1074/jbc.M110.208470. Epub 2011 Jan 17. J Biol Chem. 2011. PMID: 21242306 Free PMC article.

10

Cyclopentenyl cytosine induces senescence in breast cancer cells through the nucleolar stress response and activation of p53.

Huang M, Whang P, Lewicki P, Mitchell BS. Huang M, et al. Mol Pharmacol. 2011 Jul;80(1):40-8. doi: 10.1124/mol.110.070284. Epub 2011 Apr 4. Mol Pharmacol. 2011. PMID: 21464199 Free PMC article.

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