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1,104 results

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Page 1
Pharmacological restoration and therapeutic targeting of the B-cell phenotype in classical Hodgkin lymphoma.
Du J, Neuenschwander M, Yu Y, Däbritz JH, Neuendorff NR, Schleich K, Bittner A, Milanovic M, Beuster G, Radetzki S, Specker E, Reimann M, Rosenbauer F, Mathas S, Lohneis P, Hummel M, Dörken B, von Kries JP, Lee S, Schmitt CA. Du J, et al. Among authors: hummel m. Blood. 2017 Jan 5;129(1):71-81. doi: 10.1182/blood-2016-02-700773. Epub 2016 Oct 12. Blood. 2017. PMID: 27733358 Free article.
Classical Hodgkin lymphoma is characterized by high constitutive expression of activating transcription factor 3 (ATF3), which promotes viability of Hodgkin/Reed-Sternberg cells.
Janz M, Hummel M, Truss M, Wollert-Wulf B, Mathas S, Jöhrens K, Hagemeier C, Bommert K, Stein H, Dörken B, Bargou RC. Janz M, et al. Among authors: hummel m. Blood. 2006 Mar 15;107(6):2536-9. doi: 10.1182/blood-2005-07-2694. Epub 2005 Nov 1. Blood. 2006. PMID: 16263788 Free article.
Synthetic lethal metabolic targeting of cellular senescence in cancer therapy.
Dörr JR, Yu Y, Milanovic M, Beuster G, Zasada C, Däbritz JH, Lisec J, Lenze D, Gerhardt A, Schleicher K, Kratzat S, Purfürst B, Walenta S, Mueller-Klieser W, Gräler M, Hummel M, Keller U, Buck AK, Dörken B, Willmitzer L, Reimann M, Kempa S, Lee S, Schmitt CA. Dörr JR, et al. Among authors: hummel m. Nature. 2013 Sep 19;501(7467):421-5. doi: 10.1038/nature12437. Epub 2013 Aug 14. Nature. 2013. PMID: 23945590
Essential role of IRF4 and MYC signaling for survival of anaplastic large cell lymphoma.
Weilemann A, Grau M, Erdmann T, Merkel O, Sobhiafshar U, Anagnostopoulos I, Hummel M, Siegert A, Hayford C, Madle H, Wollert-Wulf B, Fichtner I, Dörken B, Dirnhofer S, Mathas S, Janz M, Emre NC, Rosenwald A, Ott G, Lenz P, Tzankov A, Lenz G. Weilemann A, et al. Among authors: hummel m. Blood. 2015 Jan 1;125(1):124-32. doi: 10.1182/blood-2014-08-594507. Epub 2014 Oct 30. Blood. 2015. PMID: 25359993 Free article.
Senescence-associated reprogramming promotes cancer stemness.
Milanovic M, Fan DNY, Belenki D, Däbritz JHM, Zhao Z, Yu Y, Dörr JR, Dimitrova L, Lenze D, Monteiro Barbosa IA, Mendoza-Parra MA, Kanashova T, Metzner M, Pardon K, Reimann M, Trumpp A, Dörken B, Zuber J, Gronemeyer H, Hummel M, Dittmar G, Lee S, Schmitt CA. Milanovic M, et al. Among authors: hummel m. Nature. 2018 Jan 4;553(7686):96-100. doi: 10.1038/nature25167. Epub 2017 Dec 20. Nature. 2018. PMID: 29258294
Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma.
Mathas S, Janz M, Hummel F, Hummel M, Wollert-Wulf B, Lusatis S, Anagnostopoulos I, Lietz A, Sigvardsson M, Jundt F, Jöhrens K, Bommert K, Stein H, Dörken B. Mathas S, et al. Among authors: hummel m, hummel f. Nat Immunol. 2006 Feb;7(2):207-15. doi: 10.1038/ni1285. Epub 2005 Dec 20. Nat Immunol. 2006. PMID: 16369535
Macrophage development from HSCs requires PU.1-coordinated microRNA expression.
Ghani S, Riemke P, Schönheit J, Lenze D, Stumm J, Hoogenkamp M, Lagendijk A, Heinz S, Bonifer C, Bakkers J, Abdelilah-Seyfried S, Hummel M, Rosenbauer F. Ghani S, et al. Among authors: hummel m. Blood. 2011 Aug 25;118(8):2275-84. doi: 10.1182/blood-2011-02-335141. Epub 2011 Jul 5. Blood. 2011. PMID: 21730352 Free PMC article.
Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma.
Mansouri L, Noerenberg D, Young E, Mylonas E, Abdulla M, Frick M, Asmar F, Ljungström V, Schneider M, Yoshida K, Skaftason A, Pandzic T, Gonzalez B, Tasidou A, Waldhueter N, Rivas-Delgado A, Angelopoulou M, Ziepert M, Arends CM, Couronné L, Lenze D, Baldus CD, Bastard C, Okosun J, Fitzgibbon J, Dörken B, Drexler HG, Roos-Weil D, Schmitt CA, Munch-Petersen HD, Zenz T, Hansmann ML, Strefford JC, Enblad G, Bernard OA, Ralfkiaer E, Erlanson M, Korkolopoulou P, Hultdin M, Papadaki T, Grønbæk K, Lopez-Guillermo A, Ogawa S, Küppers R, Stamatopoulos K, Stavroyianni N, Kanellis G, Rosenwald A, Campo E, Amini RM, Ott G, Vassilakopoulos TP, Hummel M, Rosenquist R, Damm F. Mansouri L, et al. Among authors: hummel m. Blood. 2016 Dec 8;128(23):2666-2670. doi: 10.1182/blood-2016-03-704528. Epub 2016 Sep 26. Blood. 2016. PMID: 27670424 Free article. Clinical Trial.
1,104 results