Crews P - Search Results

1

Identification of the First Marine-Derived Opioid Receptor "Balanced" Agonist with a Signaling Profile That Resembles the Endorphins.

Johnson TA, Milan-Lobo L, Che T, Ferwerda M, Lambu E, McIntosh NL, Li F, He L, Lorig-Roach N, Crews P, Whistler JL. Johnson TA, et al. Among authors: crews p. ACS Chem Neurosci. 2017 Mar 15;8(3):473-485. doi: 10.1021/acschemneuro.6b00167. Epub 2016 Nov 22. ACS Chem Neurosci. 2017. PMID: 27744679 Free PMC article.

2

Structures and cytotoxic properties of sponge-derived bisannulated acridines.

Thale Z, Johnson T, Tenney K, Wenzel PJ, Lobkovsky E, Clardy J, Media J, Pietraszkiewicz H, Valeriote FA, Crews P. Thale Z, et al. Among authors: crews p. J Org Chem. 2002 Dec 27;67(26):9384-91. doi: 10.1021/jo026459o. J Org Chem. 2002. PMID: 12492342

3

Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases.

Amagata T, Whitman S, Johnson TA, Stessman CC, Loo CP, Lobkovsky E, Clardy J, Crews P, Holman TR. Amagata T, et al. Among authors: crews p. J Nat Prod. 2003 Feb;66(2):230-5. doi: 10.1021/np020462l. J Nat Prod. 2003. PMID: 12608855 Free article.

4

Probing the activity differences of simple and complex brominated aryl compounds against 15-soybean, 15-human, and 12-human lipoxygenase.

Segraves EN, Shah RR, Segraves NL, Johnson TA, Whitman S, Sui JK, Kenyon VA, Cichewicz RH, Crews P, Holman TR. Segraves EN, et al. Among authors: crews p. J Med Chem. 2004 Jul 29;47(16):4060-5. doi: 10.1021/jm049872s. J Med Chem. 2004. PMID: 15267244 Free article.

5

Redox inactivation of human 15-lipoxygenase by marine-derived meroditerpenes and synthetic chromanes: archetypes for a unique class of selective and recyclable inhibitors.

Cichewicz RH, Kenyon VA, Whitman S, Morales NM, Arguello JF, Holman TR, Crews P. Cichewicz RH, et al. Among authors: crews p. J Am Chem Soc. 2004 Nov 17;126(45):14910-20. doi: 10.1021/ja046082z. J Am Chem Soc. 2004. PMID: 15535718 Free article.

6

A reassignment of (-)-mycothiazole and the isolation of a related diol.

Sonnenschein RN, Johnson TA, Tenney K, Valeriote FA, Crews P. Sonnenschein RN, et al. Among authors: crews p. J Nat Prod. 2006 Jan;69(1):145-7. doi: 10.1021/np0503597. J Nat Prod. 2006. PMID: 16441088 Free PMC article.

7

Sponge-derived fijianolide polyketide class: further evaluation of their structural and cytotoxicity properties.

Johnson TA, Tenney K, Cichewicz RH, Morinaka BI, White KN, Amagata T, Subramanian B, Media J, Mooberry SL, Valeriote FA, Crews P. Johnson TA, et al. Among authors: crews p. J Med Chem. 2007 Aug 9;50(16):3795-803. doi: 10.1021/jm070410z. Epub 2007 Jul 10. J Med Chem. 2007. PMID: 17622130 Free PMC article.

8

Discovery of platelet-type 12-human lipoxygenase selective inhibitors by high-throughput screening of structurally diverse libraries.

Deschamps JD, Gautschi JT, Whitman S, Johnson TA, Gassner NC, Crews P, Holman TR. Deschamps JD, et al. Among authors: crews p. Bioorg Med Chem. 2007 Nov 15;15(22):6900-8. doi: 10.1016/j.bmc.2007.08.015. Epub 2007 Aug 22. Bioorg Med Chem. 2007. PMID: 17826100 Free PMC article.

9

The unexpected isolation of CTP-431, a novel thiopyrone from the sponge Cacospongia mycofijiensis.

Johnson TA, Amagata T, Oliver AG, Tenney K, Valeriote FA, Crews P. Johnson TA, et al. Among authors: crews p. J Org Chem. 2008 Sep 19;73(18):7255-9. doi: 10.1021/jo801096m. Epub 2008 Aug 21. J Org Chem. 2008. PMID: 18715038

10

Interrogating the bioactive pharmacophore of the latrunculin chemotype by investigating the metabolites of two taxonomically unrelated sponges.

Amagata T, Johnson TA, Cichewicz RH, Tenney K, Mooberry SL, Media J, Edelstein M, Valeriote FA, Crews P. Amagata T, et al. Among authors: crews p. J Med Chem. 2008 Nov 27;51(22):7234-42. doi: 10.1021/jm8008585. J Med Chem. 2008. PMID: 18942825 Free PMC article.

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