Kuhn C - Search Results

1

Mucosal administration of CD3-specific monoclonal antibody inhibits diabetes in NOD mice and in a preclinical mouse model transgenic for the CD3 epsilon chain.

Kuhn C, Rezende RM, da Cunha AP, Valette F, Quintana FJ, Chatenoud L, Weiner HL. Kuhn C, et al. J Autoimmun. 2017 Jan;76:115-122. doi: 10.1016/j.jaut.2016.10.001. Epub 2016 Oct 10. J Autoimmun. 2017. PMID: 27745778 Free PMC article.

2

Human CD3 transgenic mice: preclinical testing of antibodies promoting immune tolerance.

Kuhn C, You S, Valette F, Hale G, van Endert P, Bach JF, Waldmann H, Chatenoud L. Kuhn C, et al. Sci Transl Med. 2011 Feb 2;3(68):68ra10. doi: 10.1126/scitranslmed.3001830. Sci Transl Med. 2011. PMID: 21289272

3

Regulatory mechanisms of immune tolerance in type 1 diabetes and their failures.

Kuhn C, Besançon A, Lemoine S, You S, Marquet C, Candon S, Chatenoud L. Kuhn C, et al. J Autoimmun. 2016 Jul;71:69-77. doi: 10.1016/j.jaut.2016.05.002. Epub 2016 May 21. J Autoimmun. 2016. PMID: 27216249 Review.

4

IL-6 Inhibits Upregulation of Membrane-Bound TGF-β 1 on CD4+ T Cells and Blocking IL-6 Enhances Oral Tolerance.

Kuhn C, Rezende RM, M'Hamdi H, da Cunha AP, Weiner HL. Kuhn C, et al. J Immunol. 2017 Feb 1;198(3):1202-1209. doi: 10.4049/jimmunol.1600921. Epub 2016 Dec 30. J Immunol. 2017. PMID: 28039301 Free PMC article.

5

Therapeutic anti-CD3 monoclonal antibodies: from bench to bedside.

Kuhn C, Weiner HL. Kuhn C, et al. Immunotherapy. 2016 Jul;8(8):889-906. doi: 10.2217/imt-2016-0049. Epub 2016 May 10. Immunotherapy. 2016. PMID: 27161438 Free article. Review.

6

Induction of allograft tolerance by monoclonal CD3 antibodies: a matter of timing.

You S, Zuber J, Kuhn C, Baas M, Valette F, Sauvaget V, Sarnacki S, Sawitzki B, Bach JF, Volk HD, Chatenoud L. You S, et al. Among authors: kuhn c. Am J Transplant. 2012 Nov;12(11):2909-19. doi: 10.1111/j.1600-6143.2012.04213.x. Epub 2012 Aug 6. Am J Transplant. 2012. PMID: 22882762 Free article.

7

CD3 antibodies as unique tools to restore self-tolerance in established autoimmunity their mode of action and clinical application in type 1 diabetes.

You S, Candon S, Kuhn C, Bach JF, Chatenoud L. You S, et al. Among authors: kuhn c. Adv Immunol. 2008;100:13-37. doi: 10.1016/S0065-2776(08)00802-X. Adv Immunol. 2008. PMID: 19111162 Review. No abstract available.

8

Therapeutic use of a selective S1P1 receptor modulator ponesimod in autoimmune diabetes.

You S, Piali L, Kuhn C, Steiner B, Sauvaget V, Valette F, Clozel M, Bach JF, Chatenoud L. You S, et al. Among authors: kuhn c. PLoS One. 2013 Oct 24;8(10):e77296. doi: 10.1371/journal.pone.0077296. eCollection 2013. PLoS One. 2013. PMID: 24204793 Free PMC article.

9

Combining autologous dendritic cell therapy with CD3 antibodies promotes regulatory T cells and permanent islet allograft acceptance.

Baas MC, Kuhn C, Valette F, Mangez C, Duarte MS, Hill M, Besançon A, Chatenoud L, Cuturi MC, You S. Baas MC, et al. Among authors: kuhn c. J Immunol. 2014 Nov 1;193(9):4696-703. doi: 10.4049/jimmunol.1401423. Epub 2014 Sep 24. J Immunol. 2014. PMID: 25252962

10

Oral treatment with foralumab, a fully human anti-CD3 monoclonal antibody, prevents skin xenograft rejection in humanized mice.

Ogura M, Deng S, Preston-Hurlburt P, Ogura H, Shailubhai K, Kuhn C, Weiner HL, Herold KC. Ogura M, et al. Among authors: kuhn c. Clin Immunol. 2017 Oct;183:240-246. doi: 10.1016/j.clim.2017.07.005. Epub 2017 Jul 21. Clin Immunol. 2017. PMID: 28739191

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