Zeng L - Search Results

1

Discovery of novel Ponatinib analogues for reducing KDR activity as potent FGFRs inhibitors.

Liu Y, Peng X, Guan X, Lu D, Xi Y, Jin S, Chen H, Zeng L, Ai J, Geng M, Hu Y. Liu Y, et al. Among authors: zeng l. Eur J Med Chem. 2017 Jan 27;126:122-132. doi: 10.1016/j.ejmech.2016.10.003. Epub 2016 Oct 4. Eur J Med Chem. 2017. PMID: 27750146

2

Pyridazinone derivatives displaying highly potent and selective inhibitory activities against c-Met tyrosine kinase.

Liu Y, Jin S, Peng X, Lu D, Zeng L, Sun Y, Ai J, Geng M, Hu Y. Liu Y, et al. Among authors: zeng l. Eur J Med Chem. 2016 Jan 27;108:322-333. doi: 10.1016/j.ejmech.2015.11.042. Epub 2015 Nov 30. Eur J Med Chem. 2016. PMID: 26698536

3

Discovery and optimization of phthalazinone derivatives as a new class of potent dengue virus inhibitors.

Lu D, Liu J, Zhang Y, Liu F, Zeng L, Peng R, Yang L, Ying H, Tang W, Chen W, Zuo J, Tong X, Liu T, Hu Y. Lu D, et al. Among authors: zeng l. Eur J Med Chem. 2018 Feb 10;145:328-337. doi: 10.1016/j.ejmech.2018.01.008. Epub 2018 Jan 5. Eur J Med Chem. 2018. PMID: 29335200

4

Discovery of Phthalazinone Derivatives as Novel Hepatitis B Virus Capsid Inhibitors.

Chen W, Liu F, Zhao Q, Ma X, Lu D, Li H, Zeng Y, Tong X, Zeng L, Liu J, Yang L, Zuo J, Hu Y. Chen W, et al. Among authors: zeng l, zeng y. J Med Chem. 2020 Aug 13;63(15):8134-8145. doi: 10.1021/acs.jmedchem.0c00346. Epub 2020 Jul 21. J Med Chem. 2020. PMID: 32692159

5

Design, Synthesis, and Biological Evaluation of the First c-Met/HDAC Inhibitors Based on Pyridazinone Derivatives.

Lu D, Yan J, Wang L, Liu H, Zeng L, Zhang M, Duan W, Ji Y, Cao J, Geng M, Shen A, Hu Y. Lu D, et al. Among authors: zeng l. ACS Med Chem Lett. 2017 Jul 18;8(8):830-834. doi: 10.1021/acsmedchemlett.7b00172. eCollection 2017 Aug 10. ACS Med Chem Lett. 2017. PMID: 28835797 Free PMC article.

6

Novel Class of Colony-Stimulating Factor 1 Receptor Kinase Inhibitors Based on an o-Aminopyridyl Alkynyl Scaffold as Potential Treatment for Inflammatory Disorders.

Xie Z, Wu B, Liu Y, Ren W, Tong L, Xiang C, Wei A, Gao Y, Zeng L, Xie H, Tang W, Hu Y. Xie Z, et al. Among authors: zeng l. J Med Chem. 2020 Feb 13;63(3):1397-1414. doi: 10.1021/acs.jmedchem.9b01912. Epub 2020 Jan 14. J Med Chem. 2020. PMID: 31934767

7

Discovery and optimization of 2,4-diaminoquinazoline derivatives as a new class of potent dengue virus inhibitors.

Chao B, Tong XK, Tang W, Li DW, He PL, Garcia JM, Zeng LM, Gao AH, Yang L, Li J, Nan FJ, Jacobs M, Altmeyer R, Zuo JP, Hu YH. Chao B, et al. Among authors: zeng lm. J Med Chem. 2012 Apr 12;55(7):3135-43. doi: 10.1021/jm2015952. Epub 2012 Mar 26. J Med Chem. 2012. PMID: 22448770

8

Design and synthesis of novel arctigenin analogues for the amelioration of metabolic disorders.

Duan S, Huang S, Gong J, Shen Y, Zeng L, Feng Y, Ren W, Leng Y, Hu Y. Duan S, et al. Among authors: zeng l. ACS Med Chem Lett. 2015 Mar 5;6(4):386-91. doi: 10.1021/acsmedchemlett.5b00007. eCollection 2015 Apr 9. ACS Med Chem Lett. 2015. PMID: 25941553 Free PMC article.

9

Optimization and Synthesis of Pyridazinone Derivatives as Novel Inhibitors of Hepatitis B Virus by Inducing Genome-free Capsid Formation.

Lu D, Liu F, Xing W, Tong X, Wang L, Wang Y, Zeng L, Feng C, Yang L, Zuo J, Hu Y. Lu D, et al. Among authors: zeng l. ACS Infect Dis. 2017 Mar 10;3(3):199-205. doi: 10.1021/acsinfecdis.6b00159. Epub 2016 Dec 29. ACS Infect Dis. 2017. PMID: 27989113

10

Discovery of a low-systemic-exposure DGAT-1 inhibitor with a picolinoylpyrrolidine-2-carboxylic acid moiety.

Yan J, Wang G, Dang X, Guo B, Chen W, Wang T, Zeng L, Wang H, Hu Y. Yan J, et al. Among authors: zeng l. Bioorg Med Chem. 2017 Sep 1;25(17):4701-4714. doi: 10.1016/j.bmc.2017.07.007. Epub 2017 Jul 14. Bioorg Med Chem. 2017. PMID: 28739155

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