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Page 1
The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models.
Kotschy A, Szlavik Z, Murray J, Davidson J, Maragno AL, Le Toumelin-Braizat G, Chanrion M, Kelly GL, Gong JN, Moujalled DM, Bruno A, Csekei M, Paczal A, Szabo ZB, Sipos S, Radics G, Proszenyak A, Balint B, Ondi L, Blasko G, Robertson A, Surgenor A, Dokurno P, Chen I, Matassova N, Smith J, Pedder C, Graham C, Studeny A, Lysiak-Auvity G, Girard AM, Gravé F, Segal D, Riffkin CD, Pomilio G, Galbraith LC, Aubrey BJ, Brennan MS, Herold MJ, Chang C, Guasconi G, Cauquil N, Melchiore F, Guigal-Stephan N, Lockhart B, Colland F, Hickman JA, Roberts AW, Huang DC, Wei AH, Strasser A, Lessene G, Geneste O. Kotschy A, et al. Among authors: guigal stephan n. Nature. 2016 Oct 27;538(7626):477-482. doi: 10.1038/nature19830. Epub 2016 Oct 19. Nature. 2016. PMID: 27760111
Molecular characterization of the AMPA-receptor potentiator S70340 in rat primary cortical culture: whole-genome expression profiling.
Mourlevat S, Galizzi JP, Guigal-Stéphan N, Courtade-Gaïani S, Rolland-Valognes G, Rodriguez M, Barbet F, Bourrier C, Catesson S, Chomel A, Danober L, Villain N, Caignard DH, Pirotte B, Lestage P, Lockhart BP. Mourlevat S, et al. Among authors: guigal stephan n. Neurosci Res. 2011 Aug;70(4):349-60. doi: 10.1016/j.neures.2011.05.004. Epub 2011 May 14. Neurosci Res. 2011. PMID: 21609738
A phase Ib dose allocation study of oral administration of lucitanib given in combination with fulvestrant in patients with estrogen receptor-positive and FGFR1-amplified or non-amplified metastatic breast cancer.
Campone M, Bachelot T, Penault-Llorca F, Pallis A, Agrapart V, Pierrat MJ, Poirot C, Dubois F, Xuereb L, Bossard CJ, Guigal-Stephan N, Lockhart B, Andre F. Campone M, et al. Among authors: guigal stephan n. Cancer Chemother Pharmacol. 2019 Apr;83(4):743-753. doi: 10.1007/s00280-018-03765-3. Epub 2019 Jan 25. Cancer Chemother Pharmacol. 2019. PMID: 30684019 Clinical Trial.
Coordinate Transcriptomic and Metabolomic Effects of the Insulin Sensitizer Rosiglitazone on Fundamental Metabolic Pathways in Liver, Soleus Muscle, and Adipose Tissue in Diabetic db/db Mice.
Le Bouter S, Rodriguez M, Guigal-Stephan N, Courtade-Gaïani S, Xuereb L, de Montrion C, Croixmarie V, Umbdenstock T, Boursier-Neyret C, Lonchampt M, Brun M, Dacquet C, Ktorza A, Lockhart BP, Galizzi JP. Le Bouter S, et al. Among authors: guigal stephan n. PPAR Res. 2010;2010:679184. doi: 10.1155/2010/679184. Epub 2010 Oct 10. PPAR Res. 2010. PMID: 20953342 Free PMC article.