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339 results

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Page 1
The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models.
Kotschy A, Szlavik Z, Murray J, Davidson J, Maragno AL, Le Toumelin-Braizat G, Chanrion M, Kelly GL, Gong JN, Moujalled DM, Bruno A, Csekei M, Paczal A, Szabo ZB, Sipos S, Radics G, Proszenyak A, Balint B, Ondi L, Blasko G, Robertson A, Surgenor A, Dokurno P, Chen I, Matassova N, Smith J, Pedder C, Graham C, Studeny A, Lysiak-Auvity G, Girard AM, Gravé F, Segal D, Riffkin CD, Pomilio G, Galbraith LC, Aubrey BJ, Brennan MS, Herold MJ, Chang C, Guasconi G, Cauquil N, Melchiore F, Guigal-Stephan N, Lockhart B, Colland F, Hickman JA, Roberts AW, Huang DC, Wei AH, Strasser A, Lessene G, Geneste O. Kotschy A, et al. Among authors: roberts aw. Nature. 2016 Oct 27;538(7626):477-482. doi: 10.1038/nature19830. Epub 2016 Oct 19. Nature. 2016. PMID: 27760111
Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic.
Kuroda J, Puthalakath H, Cragg MS, Kelly PN, Bouillet P, Huang DC, Kimura S, Ottmann OG, Druker BJ, Villunger A, Roberts AW, Strasser A. Kuroda J, et al. Among authors: roberts aw. Proc Natl Acad Sci U S A. 2006 Oct 3;103(40):14907-12. doi: 10.1073/pnas.0606176103. Epub 2006 Sep 22. Proc Natl Acad Sci U S A. 2006. PMID: 16997913 Free PMC article.
Programmed anuclear cell death delimits platelet life span.
Mason KD, Carpinelli MR, Fletcher JI, Collinge JE, Hilton AA, Ellis S, Kelly PN, Ekert PG, Metcalf D, Roberts AW, Huang DC, Kile BT. Mason KD, et al. Among authors: roberts aw. Cell. 2007 Mar 23;128(6):1173-86. doi: 10.1016/j.cell.2007.01.037. Cell. 2007. PMID: 17382885 Free article.
Bortezomib: putting mantle cell lymphoma on death row.
Wei AH, Roberts AW. Wei AH, et al. Among authors: roberts aw. Leuk Lymphoma. 2008 Apr;49(4):657-8. doi: 10.1080/10428190801942378. Leuk Lymphoma. 2008. PMID: 18398731 Review. No abstract available.
Two distinct pathways regulate platelet phosphatidylserine exposure and procoagulant function.
Schoenwaelder SM, Yuan Y, Josefsson EC, White MJ, Yao Y, Mason KD, O'Reilly LA, Henley KJ, Ono A, Hsiao S, Willcox A, Roberts AW, Huang DC, Salem HH, Kile BT, Jackson SP. Schoenwaelder SM, et al. Among authors: roberts aw. Blood. 2009 Jul 16;114(3):663-6. doi: 10.1182/blood-2009-01-200345. Epub 2009 Apr 22. Blood. 2009. PMID: 19387006 Free article.
BH3-mimetics--the solution to chemoresistance?
Khaw SL, Huang DC, Roberts AW. Khaw SL, et al. Among authors: roberts aw. Leuk Lymphoma. 2009 Jul;50(7):1069-72. doi: 10.1080/10428190903015644. Leuk Lymphoma. 2009. PMID: 19557627 No abstract available.
Structural basis for apoptosis inhibition by Epstein-Barr virus BHRF1.
Kvansakul M, Wei AH, Fletcher JI, Willis SN, Chen L, Roberts AW, Huang DC, Colman PM. Kvansakul M, et al. Among authors: roberts aw. PLoS Pathog. 2010 Dec 23;6(12):e1001236. doi: 10.1371/journal.ppat.1001236. PLoS Pathog. 2010. PMID: 21203485 Free PMC article.
339 results