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Characterization of the novel mutant A78T-HERG from a long QT syndrome type 2 patient: Instability of the mutant protein and stabilization by heat shock factor 1.
Kondo T, Hisatome I, Yoshimura S, Mahati E, Notsu T, Li P, Iitsuka K, Kato M, Ogura K, Miake J, Aiba T, Shimizu W, Kurata Y, Sakata S, Nakasone N, Ninomiya H, Nakai A, Higaki K, Kawata Y, Shirayoshi Y, Yoshida A, Yamamoto K. Kondo T, et al. Among authors: sakata s. J Arrhythm. 2016 Oct;32(5):433-440. doi: 10.1016/j.joa.2015.10.005. Epub 2015 Nov 25. J Arrhythm. 2016. PMID: 27761169 Free PMC article.
Instability of KCNE1-D85N that causes long QT syndrome: stabilization by verapamil.
Sakata S, Kurata Y, Li P, Notsu T, Morikawa K, Miake J, Higaki K, Yamamoto Y, Yoshida A, Shirayoshi Y, Yamamoto K, Horie M, Ninomiya H, Kanzaki S, Hisatome I. Sakata S, et al. Pacing Clin Electrophysiol. 2014 Jul;37(7):853-63. doi: 10.1111/pace.12360. Epub 2014 Feb 5. Pacing Clin Electrophysiol. 2014. PMID: 24499369
M3 Muscarinic Receptor Signaling Stabilizes a Novel Mutant Human Ether-a-Go-Go-Related Gene Channel Protein via Phosphorylation of Heat Shock Factor 1 in Transfected Cells.
Mahati E, Li P, Kurata Y, Maharani N, Ikeda N, Sakata S, Ogura K, Miake J, Aiba T, Shimizu W, Nakasone N, Ninomiya H, Higaki K, Yamamoto K, Nakai A, Shirayoshi Y, Hisatome I. Mahati E, et al. Among authors: sakata s. Circ J. 2016 Nov 25;80(12):2443-2452. doi: 10.1253/circj.CJ-16-0712. Epub 2016 Nov 1. Circ J. 2016. PMID: 27803431 Free article.
Simultaneous treatment with azelnidipine and olmesartan inhibits apoptosis of Hl-1 cardiac myocytes expressing E334k cMyBPC.
Bahrudin U, Ikeda N, Utami SB, Maharani N, Morikawa K, Li P, Sobirin MA, Hasegawa A, Sakata S, Endo R, Rifqi S, Shirayoshi Y, Yamamoto K, Ninomiya H, Hisatome I. Bahrudin U, et al. Among authors: sakata s. Drug Res (Stuttg). 2013 Oct;63(10):515-20. doi: 10.1055/s-0033-1347188. Epub 2013 Jun 5. Drug Res (Stuttg). 2013. PMID: 23740383
Effects of cilnidipine on serum uric acid level and urinary nitrogen monoxide excretion in patients with hypertension.
Hamada T, Yamada K, Mizuta E, Watanabe A, Osaki T, Ishida K, Hasegawa A, Sakata S, Mishima M, Ogino K, Nosaka Y, Miyazaki S, Ohtahara A, Ninomiya H, Kato M, Yoshida A, Taniguchi S, Yamamoto K, Hisatome I. Hamada T, et al. Among authors: sakata s. Clin Exp Hypertens. 2012;34(7):470-3. doi: 10.3109/10641963.2012.666600. Epub 2012 Jun 8. Clin Exp Hypertens. 2012. PMID: 22681507 Free article.
Fluctuating liver functions in siblings with MPV17 mutations and possible improvement associated with dietary and pharmaceutical treatments targeting respiratory chain complex II.
Kaji S, Murayama K, Nagata I, Nagasaka H, Takayanagi M, Ohtake A, Iwasa H, Nishiyama M, Okazaki Y, Harashima H, Eitoku T, Yamamoto M, Matsushita H, Kitamoto K, Sakata S, Katayama T, Sugimoto S, Fujimoto Y, Murakami J, Kanzaki S, Shiraki K. Kaji S, et al. Among authors: sakata s. Mol Genet Metab. 2009 Aug;97(4):292-6. doi: 10.1016/j.ymgme.2009.04.014. Epub 2009 May 12. Mol Genet Metab. 2009. PMID: 19520594
1,022 results