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ATP-competitive inhibitors of PI3K enzymes demonstrate an isoform selective dual action by controlling membrane binding.
Gong GQ, Masson GR, Lee WJ, Dickson JMJ, Kendall JD, Rathinaswamy MK, Buchanan CM, Middleditch M, Owen BM, Spicer JA, Rewcastle GW, Denny WA, Burke JE, Shepherd PR, Williams RL, Flanagan JU. Gong GQ, et al. Among authors: shepherd pr. Biochem J. 2024 Dec 4;481(23):1787-1802. doi: 10.1042/BCJ20240479. Biochem J. 2024. PMID: 39485310 Free PMC article.
The population-specific Thr44Met OCT3 coding variant affects metformin pharmacokinetics with subsequent effects on insulin sensitivity in C57Bl/6J mice.
Wang Q, Leask MP, Lee K, Jaiswal J, Kallingappa P, Dissanayake W, Puli'uvea C, O'Sullivan C, Watson H, Wilcox P, Murphy R, Merry TL, Shepherd PR. Wang Q, et al. Among authors: shepherd pr. Diabetologia. 2024 Oct 18. doi: 10.1007/s00125-024-06287-1. Online ahead of print. Diabetologia. 2024. PMID: 39422716
Integrative Molecular Analyses of the MD Anderson Prostate Cancer Patient-derived Xenograft (MDA PCa PDX) Series.
Anselmino N, Labanca E, Shepherd PDA, Dong J, Yang J, Song X, Nandakumar S, Kundra R, Lee C, Schultz N, Zhang J, Araujo JC, Aparicio AM, Subudhi SK, Corn PG, Pisters LL, Ward JF, Davis JW, Vazquez ES, Gueron G, Logothetis CJ, Futreal A, Troncoso P, Chen Y, Navone NM. Anselmino N, et al. Among authors: shepherd pda. Clin Cancer Res. 2024 May 15;30(10):2272-2285. doi: 10.1158/1078-0432.CCR-23-2438. Clin Cancer Res. 2024. PMID: 38488813 Free PMC article.
Author Correction: Aerial additive manufacturing with multiple autonomous robots.
Zhang K, Chermprayong P, Xiao F, Tzoumanikas D, Dams B, Kay S, Kocer BB, Burns A, Orr L, Alhinai T, Choi C, Darekar DD, Li W, Hirschmann S, Soana V, Ngah SA, Grillot C, Sareh S, Choubey A, Margheri L, Pawar VM, Ball RJ, Williams C, Shepherd P, Leutenegger S, Stuart-Smith R, Kovac M. Zhang K, et al. Among authors: shepherd p. Nature. 2024 Feb;626(7998):E5. doi: 10.1038/s41586-024-07030-x. Nature. 2024. PMID: 38263518 No abstract available.
363 results