Troth S - Search Results

1

Graphical display of histopathology data from toxicology studies for drug discovery and development: An industry perspective.

Brown AP, Drew P, Knight B, Marc P, Troth S, Wuersch K, Zandee J. Brown AP, et al. Among authors: troth s. Regul Toxicol Pharmacol. 2016 Dec;82:167-172. doi: 10.1016/j.yrtph.2016.10.009. Epub 2016 Oct 18. Regul Toxicol Pharmacol. 2016. PMID: 27769829

2

Magnitude of Urine Albumin and KIM-1 Changes Can be Used to Differentiate Glomerular Injury From Tubular Injury in Rats.

Gu YZ, Paul E, Vlasakova K, Troth SP, Sistare FD, Ramaiah L, Potz O, Sutradhar S, Glaab WE. Gu YZ, et al. Among authors: troth sp. Toxicol Pathol. 2024 Feb;52(2-3):88-98. doi: 10.1177/01926233241248656. Epub 2024 May 14. Toxicol Pathol. 2024. PMID: 38742644 Free PMC article.

3

In vivo CXCR4 expression, lymphoid cell phenotype, and feline immunodeficiency virus infection.

Troth SP, Dean AD, Hoover EA. Troth SP, et al. Vet Immunol Immunopathol. 2008 May 15;123(1-2):97-105. doi: 10.1016/j.vetimm.2008.01.015. Epub 2008 Jan 19. Vet Immunol Immunopathol. 2008. PMID: 18295345 Free PMC article.

4

Scientific and Regulatory Policy Committee Points to Consider: Data Visualization for Clinical and Anatomic Pathologists.

Troth SP, Everds NE, Siska W, Knight B, Lamb M, Hutt J. Troth SP, et al. Toxicol Pathol. 2018 Jul;46(5):476-487. doi: 10.1177/0192623318778733. Epub 2018 May 29. Toxicol Pathol. 2018. PMID: 29843574 Review.

5

Do longer duration nonclinical toxicology studies provide predictive clinical safety value? The IQ consortium longer duration nonclinical to clinical translational database.

Monticello TM, Potter DM, Huang Q, Hart TK, Shuey D, Troth S, Vergis JM, Tassew N, Glascott P. Monticello TM, et al. Among authors: troth s. Toxicol Appl Pharmacol. 2024 Nov;492:117087. doi: 10.1016/j.taap.2024.117087. Epub 2024 Sep 5. Toxicol Appl Pharmacol. 2024. PMID: 39243825

6

Kidney Safety Assessment: Current Practices in Drug Development.

Troth SP, Simutis F, Friedman GS, Todd S, Sistare FD. Troth SP, et al. Semin Nephrol. 2019 Mar;39(2):120-131. doi: 10.1016/j.semnephrol.2018.12.002. Semin Nephrol. 2019. PMID: 30827335 Review.

7

Scientific and Regulatory Policy Committee Points to Consider: Review of the United States Food and Drug Administration (FDA) Guidance on Pathology Peer Review in Nonclinical Toxicology Studies.

McDorman KS, Bennet BM, Colman K, Fikes JD, Keirstead ND, Lanning Retired L, Munch B, Romeike A, Schafer KA, Schorsch F, Thibodeau MS, Thomas HC, Troth S, Vahle JL, Geoly FJ. McDorman KS, et al. Among authors: troth s. Toxicol Pathol. 2024 Feb;52(2-3):138-148. doi: 10.1177/01926233241248654. Epub 2024 Jun 6. Toxicol Pathol. 2024. PMID: 38840532 Review.

8

Scientific and Regulatory Policy Committee Points to Consider*: Approaches to the Conduct and Interpretation of Vaccine Safety Studies for Clinical and Anatomic Pathologists.

Sellers RS, Nelson K, Bennet B, Wolf J, Tripathi N, Chamanza R, Perron Lepage MF, Adkins K, Laurent S, Troth SP. Sellers RS, et al. Among authors: troth sp. Toxicol Pathol. 2020 Feb;48(2):257-276. doi: 10.1177/0192623319875085. Epub 2019 Oct 8. Toxicol Pathol. 2020. PMID: 31594486

9

Towards consensus practices to qualify safety biomarkers for use in early drug development.

Sistare FD, Dieterle F, Troth S, Holder DJ, Gerhold D, Andrews-Cleavenger D, Baer W, Betton G, Bounous D, Carl K, Collins N, Goering P, Goodsaid F, Gu YZ, Guilpin V, Harpur E, Hassan A, Jacobson-Kram D, Kasper P, Laurie D, Lima BS, Maciulaitis R, Mattes W, Maurer G, Obert LA, Ozer J, Papaluca-Amati M, Phillips JA, Pinches M, Schipper MJ, Thompson KL, Vamvakas S, Vidal JM, Vonderscher J, Walker E, Webb C, Yu Y. Sistare FD, et al. Among authors: troth s. Nat Biotechnol. 2010 May;28(5):446-54. doi: 10.1038/nbt.1634. Epub 2010 May 10. Nat Biotechnol. 2010. PMID: 20458314

10

Recommendations for the evaluation of pathology data in nonclinical safety biomarker qualification studies.

Burkhardt JE, Pandher K, Solter PF, Troth SP, Boyce RW, Zabka TS, Ennulat D. Burkhardt JE, et al. Among authors: troth sp. Toxicol Pathol. 2011 Dec;39(7):1129-37. doi: 10.1177/0192623311422082. Toxicol Pathol. 2011. PMID: 22116771

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