Jahn SC - Search Results

1

Therapeutic applications of dichloroacetate and the role of glutathione transferase zeta-1.

James MO, Jahn SC, Zhong G, Smeltz MG, Hu Z, Stacpoole PW. James MO, et al. Among authors: jahn sc. Pharmacol Ther. 2017 Feb;170:166-180. doi: 10.1016/j.pharmthera.2016.10.018. Epub 2016 Oct 19. Pharmacol Ther. 2017. PMID: 27771434 Free PMC article. Review.

2

Chloride concentrations in human hepatic cytosol and mitochondria are a function of age.

Jahn SC, Rowland-Faux L, Stacpoole PW, James MO. Jahn SC, et al. Biochem Biophys Res Commun. 2015 Apr 10;459(3):463-8. doi: 10.1016/j.bbrc.2015.02.128. Epub 2015 Mar 3. Biochem Biophys Res Commun. 2015. PMID: 25748576 Free PMC article.

3

GSTZ1 expression and chloride concentrations modulate sensitivity of cancer cells to dichloroacetate.

Jahn SC, Solayman MH, Lorenzo RJ, Langaee T, Stacpoole PW, James MO. Jahn SC, et al. Biochim Biophys Acta. 2016 Jun;1860(6):1202-10. doi: 10.1016/j.bbagen.2016.01.024. Epub 2016 Feb 2. Biochim Biophys Acta. 2016. PMID: 26850694 Free PMC article.

4

Regulation of dichloroacetate biotransformation in rat liver and extrahepatic tissues by GSTZ1 expression and chloride concentration.

Jahn SC, Smeltz MG, Hu Z, Rowland-Faux L, Zhong G, Lorenzo RJ, Cisneros KV, Stacpoole PW, James MO. Jahn SC, et al. Biochem Pharmacol. 2018 Jun;152:236-243. doi: 10.1016/j.bcp.2018.04.001. Epub 2018 Apr 5. Biochem Pharmacol. 2018. PMID: 29626439 Free PMC article.

5

Zhong G, James MO, Smeltz MG, Jahn SC, Langaee T, Simpson P, Stacpoole PW. Zhong G, et al. Among authors: jahn sc. Drug Metab Dispos. 2018 Aug;46(8):1118-1128. doi: 10.1124/dmd.118.081810. Epub 2018 May 31. Drug Metab Dispos. 2018. PMID: 29853471 Free PMC article.

6

Mitochondrial Glutathione Transferase Zeta 1 Is Inactivated More Rapidly by Dichloroacetate than the Cytosolic Enzyme in Adult and Juvenile Rat Liver.

Smeltz MG, Hu Z, Zhong G, Jahn SC, Rowland-Faux L, Horne LP, Stacpoole PW, James MO. Smeltz MG, et al. Among authors: jahn sc. Chem Res Toxicol. 2019 Oct 21;32(10):2042-2052. doi: 10.1021/acs.chemrestox.9b00207. Epub 2019 Oct 1. Chem Res Toxicol. 2019. PMID: 31524376 Free PMC article.

7

Age-Related Changes in miRNA Expression Influence GSTZ1 and Other Drug Metabolizing Enzymes.

Jahn SC, Gay LA, Weaver CJ, Renne R, Langaee TY, Stacpoole PW, James MO. Jahn SC, et al. Drug Metab Dispos. 2020 Jul;48(7):563-569. doi: 10.1124/dmd.120.090639. Epub 2020 May 1. Drug Metab Dispos. 2020. PMID: 32357971 Free PMC article.

8

TGF-beta antiproliferative effects in tumor suppression.

Jahn SC, Law ME, Corsino PE, Law BK. Jahn SC, et al. Front Biosci (Schol Ed). 2012 Jan 1;4(2):749-66. doi: 10.2741/s297. Front Biosci (Schol Ed). 2012. PMID: 22202088 Free article. Review.

9

Small-molecule inhibitors of acetyltransferase p300 identified by high-throughput screening are potent anticancer agents.

Yang H, Pinello CE, Luo J, Li D, Wang Y, Zhao LY, Jahn SC, Saldanha SA, Chase P, Planck J, Geary KR, Ma H, Law BK, Roush WR, Hodder P, Liao D. Yang H, et al. Among authors: jahn sc. Mol Cancer Ther. 2013 May;12(5):610-20. doi: 10.1158/1535-7163.MCT-12-0930. Epub 2013 Apr 26. Mol Cancer Ther. 2013. PMID: 23625935 Free PMC article.

10

Repurposing Tranexamic Acid as an Anticancer Agent.

Law ME, Davis BJ, Ghilardi AF, Yaaghubi E, Dulloo ZM, Wang M, Guryanova OA, Heldermon CD, Jahn SC, Castellano RK, Law BK. Law ME, et al. Among authors: jahn sc. Front Pharmacol. 2022 Jan 13;12:792600. doi: 10.3389/fphar.2021.792600. eCollection 2021. Front Pharmacol. 2022. PMID: 35095503 Free PMC article.

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