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Page 1
The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts.
Saini N, Roberts SA, Klimczak LJ, Chan K, Grimm SA, Dai S, Fargo DC, Boyer JC, Kaufmann WK, Taylor JA, Lee E, Cortes-Ciriano I, Park PJ, Schurman SH, Malc EP, Mieczkowski PA, Gordenin DA. Saini N, et al. Among authors: grimm sa. PLoS Genet. 2016 Oct 27;12(10):e1006385. doi: 10.1371/journal.pgen.1006385. eCollection 2016 Oct. PLoS Genet. 2016. PMID: 27788131 Free PMC article. Clinical Trial.
An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers.
Roberts SA, Lawrence MS, Klimczak LJ, Grimm SA, Fargo D, Stojanov P, Kiezun A, Kryukov GV, Carter SL, Saksena G, Harris S, Shah RR, Resnick MA, Getz G, Gordenin DA. Roberts SA, et al. Among authors: grimm sa. Nat Genet. 2013 Sep;45(9):970-6. doi: 10.1038/ng.2702. Epub 2013 Jul 14. Nat Genet. 2013. PMID: 23852170 Free PMC article.
Revealing a human p53 universe.
Nguyen TT, Grimm SA, Bushel PR, Li J, Li Y, Bennett BD, Lavender CA, Ward JM, Fargo DC, Anderson CW, Li L, Resnick MA, Menendez D. Nguyen TT, et al. Among authors: grimm sa. Nucleic Acids Res. 2018 Sep 19;46(16):8153-8167. doi: 10.1093/nar/gky720. Nucleic Acids Res. 2018. PMID: 30107566 Free PMC article.
Crohn's disease IRGM risk alleles are associated with altered gene expression in human tissues.
Ajayi TA, Innes CL, Grimm SA, Rai P, Finethy R, Coers J, Wang X, Bell DA, McGrath JA, Schurman SH, Fessler MB. Ajayi TA, et al. Among authors: grimm sa. Am J Physiol Gastrointest Liver Physiol. 2019 Jan 1;316(1):G95-G105. doi: 10.1152/ajpgi.00196.2018. Epub 2018 Oct 18. Am J Physiol Gastrointest Liver Physiol. 2019. PMID: 30335469 Free PMC article.
DNA methylation in mice is influenced by genetics as well as sex and life experience.
Grimm SA, Shimbo T, Takaku M, Thomas JW, Auerbach S, Bennett BD, Bucher JR, Burkholder AB, Day F, Du Y, Duncan CG, French JE, Foley JF, Li J, Merrick BA, Tice RR, Wang T, Xu X; NISC Comparative Sequencing Program; Bushel PR, Fargo DC, Mullikin JC, Wade PA. Grimm SA, et al. Nat Commun. 2019 Jan 18;10(1):305. doi: 10.1038/s41467-018-08067-z. Nat Commun. 2019. PMID: 30659182 Free PMC article.
MBD3 localizes at promoters, gene bodies and enhancers of active genes.
Shimbo T, Du Y, Grimm SA, Dhasarathy A, Mav D, Shah RR, Shi H, Wade PA. Shimbo T, et al. Among authors: grimm sa. PLoS Genet. 2013;9(12):e1004028. doi: 10.1371/journal.pgen.1004028. Epub 2013 Dec 26. PLoS Genet. 2013. PMID: 24385926 Free PMC article.
94 results