Lortat-Jacob H - Search Results

1

A Cinnamon-Derived Procyanidin Compound Displays Anti-HIV-1 Activity by Blocking Heparan Sulfate- and Co-Receptor- Binding Sites on gp120 and Reverses T Cell Exhaustion via Impeding Tim-3 and PD-1 Upregulation.

Connell BJ, Chang SY, Prakash E, Yousfi R, Mohan V, Posch W, Wilflingseder D, Moog C, Kodama EN, Clayette P, Lortat-Jacob H. Connell BJ, et al. PLoS One. 2016 Oct 27;11(10):e0165386. doi: 10.1371/journal.pone.0165386. eCollection 2016. PLoS One. 2016. PMID: 27788205 Free PMC article.

2

Heparan sulfate targets the HIV-1 envelope glycoprotein gp120 coreceptor binding site.

Vivès RR, Imberty A, Sattentau QJ, Lortat-Jacob H. Vivès RR, et al. J Biol Chem. 2005 Jun 3;280(22):21353-7. doi: 10.1074/jbc.M500911200. Epub 2005 Mar 28. J Biol Chem. 2005. PMID: 15797855 Free article.

3

Interferon and heparan sulphate.

Lortat-Jacob H. Lortat-Jacob H. Biochem Soc Trans. 2006 Jun;34(Pt 3):461-4. doi: 10.1042/BST0340461. Biochem Soc Trans. 2006. PMID: 16709188 Review.

4

The HIV-1 envelope glycoprotein gp120 features four heparan sulfate binding domains, including the co-receptor binding site.

Crublet E, Andrieu JP, Vivès RR, Lortat-Jacob H. Crublet E, et al. J Biol Chem. 2008 May 30;283(22):15193-200. doi: 10.1074/jbc.M800066200. Epub 2008 Mar 31. J Biol Chem. 2008. PMID: 18378683 Free PMC article.

5

A synthetic CD4-heparan sulfate glycoconjugate inhibits CCR5 and CXCR4 HIV-1 attachment and entry.

Baleux F, Loureiro-Morais L, Hersant Y, Clayette P, Arenzana-Seisdedos F, Bonnaffé D, Lortat-Jacob H. Baleux F, et al. Nat Chem Biol. 2009 Oct;5(10):743-8. doi: 10.1038/nchembio.207. Epub 2009 Sep 6. Nat Chem Biol. 2009. PMID: 19734912

6

A synthetic heparan sulfate-mimetic peptide conjugated to a mini CD4 displays very high anti- HIV-1 activity independently of coreceptor usage.

Connell BJ, Baleux F, Coic YM, Clayette P, Bonnaffé D, Lortat-Jacob H. Connell BJ, et al. Chem Biol. 2012 Jan 27;19(1):131-9. doi: 10.1016/j.chembiol.2011.12.009. Chem Biol. 2012. PMID: 22284360

7

Human immunodeficiency virus and heparan sulfate: from attachment to entry inhibition.

Connell BJ, Lortat-Jacob H. Connell BJ, et al. Front Immunol. 2013 Nov 20;4:385. doi: 10.3389/fimmu.2013.00385. Front Immunol. 2013. PMID: 24312095 Free PMC article. Review.

8

CD4-mimetic sulfopeptide conjugates display sub-nanomolar anti-HIV-1 activity and protect macaques against a SHIV162P3 vaginal challenge.

Ariën KK, Baleux F, Desjardins D, Porrot F, Coïc YM, Michiels J, Bouchemal K, Bonnaffé D, Bruel T, Schwartz O, Le Grand R, Vanham G, Dereuddre-Bosquet N, Lortat-Jacob H. Ariën KK, et al. Sci Rep. 2016 Oct 10;6:34829. doi: 10.1038/srep34829. Sci Rep. 2016. PMID: 27721488 Free PMC article.

9

Heparan sulfate differentially controls CXCL12α- and CXCL12γ-mediated cell migration through differential presentation to their receptor CXCR4.

Connell BJ, Sadir R, Baleux F, Laguri C, Kleman JP, Luo L, Arenzana-Seisdedos F, Lortat-Jacob H. Connell BJ, et al. Sci Signal. 2016 Nov 1;9(452):ra107. doi: 10.1126/scisignal.aaf1839. Sci Signal. 2016. PMID: 27803285

10

CCR5 structural plasticity shapes HIV-1 phenotypic properties.

Colin P, Zhou Z, Staropoli I, Garcia-Perez J, Gasser R, Armani-Tourret M, Benureau Y, Gonzalez N, Jin J, Connell BJ, Raymond S, Delobel P, Izopet J, Lortat-Jacob H, Alcami J, Arenzana-Seisdedos F, Brelot A, Lagane B. Colin P, et al. PLoS Pathog. 2018 Dec 6;14(12):e1007432. doi: 10.1371/journal.ppat.1007432. eCollection 2018 Dec. PLoS Pathog. 2018. PMID: 30521629 Free PMC article.

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