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Page 1
Mechanistic Insights of an Immunological Adverse Event Induced by an Anti-KIT Antibody Drug Conjugate and Mitigation Strategies.
L'Italien L, Orozco O, Abrams T, Cantagallo L, Connor A, Desai J, Ebersbach H, Gelderblom H, Hoffmaster K, Lees E, Maacke H, Schleyer S, Skegro D, Lee-Hoeflich ST. L'Italien L, et al. Among authors: ebersbach h. Clin Cancer Res. 2018 Jul 15;24(14):3465-3474. doi: 10.1158/1078-0432.CCR-17-3786. Epub 2018 Apr 3. Clin Cancer Res. 2018. PMID: 29615457
Therapeutic potential of macrophage colony-stimulating factor in chronic liver disease.
Keshvari S, Genz B, Teakle N, Caruso M, Cestari MF, Patkar OL, Tse BWC, Sokolowski KA, Ebersbach H, Jascur J, MacDonald KPA, Miller G, Ramm GA, Pettit AR, Clouston AD, Powell EE, Hume DA, Irvine KM. Keshvari S, et al. Among authors: ebersbach h. Dis Model Mech. 2022 Apr 1;15(4):dmm049387. doi: 10.1242/dmm.049387. Epub 2022 Apr 19. Dis Model Mech. 2022. PMID: 35169835 Free PMC article.
Bone overgrowth-associated mutations in the LRP4 gene impair sclerostin facilitator function.
Leupin O, Piters E, Halleux C, Hu S, Kramer I, Morvan F, Bouwmeester T, Schirle M, Bueno-Lozano M, Fuentes FJ, Itin PH, Boudin E, de Freitas F, Jennes K, Brannetti B, Charara N, Ebersbach H, Geisse S, Lu CX, Bauer A, Van Hul W, Kneissel M. Leupin O, et al. Among authors: ebersbach h. J Biol Chem. 2011 Jun 3;286(22):19489-500. doi: 10.1074/jbc.M110.190330. Epub 2011 Apr 6. J Biol Chem. 2011. PMID: 21471202 Free PMC article.
Targeting interleukin-4 to the arthritic joint.
Spieler V, Ludwig MG, Dawson J, Tigani B, Littlewood-Evans A, Safina C, Ebersbach H, Seuwen K, Raschig M, Ter Mors B, Müller TD, Meinel L, Lühmann T. Spieler V, et al. Among authors: ebersbach h. J Control Release. 2020 Oct 10;326:172-180. doi: 10.1016/j.jconrel.2020.07.005. Epub 2020 Jul 10. J Control Release. 2020. PMID: 32653504
ADA2 is a lysosomal deoxyadenosine deaminase acting on DNA involved in regulating TLR9-mediated immune sensing of DNA.
Greiner-Tollersrud OK, Krausz M, Boehler V, Polyzou A, Seidl M, Spahiu A, Abdullah Z, Andryka-Cegielski K, Dominick FI, Huebscher K, Goschin A, Smulski CR, Trompouki E, Link R, Ebersbach H, Srinivas H, Marchant M, Sogkas G, Staab D, Vågbø C, Guerini D, Baasch S, Latz E, Hartmann G, Henneke P, Geiger R, Peng XP, Grimbacher B, Bartok E, Alseth I, Warncke M, Proietti M. Greiner-Tollersrud OK, et al. Among authors: ebersbach h. Cell Rep. 2024 Nov 26;43(11):114899. doi: 10.1016/j.celrep.2024.114899. Epub 2024 Oct 22. Cell Rep. 2024. PMID: 39441717 Free article.
IOS-1002, a Stabilized HLA-B57 Open Format, Exerts Potent Anti-Tumor Activity.
Rafiei A, Gualandi M, Yang CL, Woods R, Kumar A, Brunner K, Sigrist J, Ebersbach H, Coats S, Renner C, Marroquin Belaunzaran O. Rafiei A, et al. Among authors: ebersbach h. Cancers (Basel). 2024 Aug 21;16(16):2902. doi: 10.3390/cancers16162902. Cancers (Basel). 2024. PMID: 39199672 Free PMC article.
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