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Baseline MAPK signaling activity confers intrinsic radioresistance to KRAS-mutant colorectal carcinoma cells by rapid upregulation of heterogeneous nuclear ribonucleoprotein K (hnRNP K).
Eder S, Arndt A, Lamkowski A, Daskalaki W, Rump A, Priller M, Genze F, Wardelmann E, Port M, Steinestel K. Eder S, et al. Among authors: wardelmann e. Cancer Lett. 2017 Jan 28;385:160-167. doi: 10.1016/j.canlet.2016.10.027. Epub 2016 Oct 25. Cancer Lett. 2017. PMID: 27793696
Phosphatidylinositol-3'-kinase/AKT signaling is essential in synovial sarcoma.
Friedrichs N, Trautmann M, Endl E, Sievers E, Kindler D, Wurst P, Czerwitzki J, Steiner S, Renner M, Penzel R, Koch A, Larsson O, Tanaka S, Kawai A, Schirmacher P, Mechtersheimer G, Wardelmann E, Buettner R, Hartmann W. Friedrichs N, et al. Among authors: wardelmann e. Int J Cancer. 2011 Oct 1;129(7):1564-75. doi: 10.1002/ijc.25829. Epub 2011 Mar 4. Int J Cancer. 2011. PMID: 21128248
SRC signaling is crucial in the growth of synovial sarcoma cells.
Michels S, Trautmann M, Sievers E, Kindler D, Huss S, Renner M, Friedrichs N, Kirfel J, Steiner S, Endl E, Wurst P, Heukamp L, Penzel R, Larsson O, Kawai A, Tanaka S, Sonobe H, Schirmacher P, Mechtersheimer G, Wardelmann E, Büttner R, Hartmann W. Michels S, et al. Among authors: wardelmann e. Cancer Res. 2013 Apr 15;73(8):2518-28. doi: 10.1158/0008-5472.CAN-12-3023. Epub 2013 Apr 11. Cancer Res. 2013. PMID: 23580575
Regulators of Actin Dynamics in Gastrointestinal Tract Tumors.
Steinestel K, Wardelmann E, Hartmann W, Grünewald I. Steinestel K, et al. Among authors: wardelmann e. Gastroenterol Res Pract. 2015;2015:930157. doi: 10.1155/2015/930157. Epub 2015 Aug 4. Gastroenterol Res Pract. 2015. PMID: 26345720 Free PMC article. Review.
Erratum to: The small conductance calcium-activated potassium channel 3 (SK3) is a molecular target for Edelfosine to reduce the invasive potential of urothelial carcinoma cells.
Steinestel K, Eder S, Ehinger K, Schneider J, Genze F, Winkler E, Wardelmann E, Schrader AJ, Steinestel J. Steinestel K, et al. Among authors: wardelmann e. Tumour Biol. 2016 Feb;37(2):2773. doi: 10.1007/s13277-015-4659-5. Tumour Biol. 2016. PMID: 26711779 No abstract available.
FUS-DDIT3 Fusion Protein-Driven IGF-IR Signaling is a Therapeutic Target in Myxoid Liposarcoma.
Trautmann M, Menzel J, Bertling C, Cyra M, Isfort I, Steinestel K, Elges S, Grünewald I, Altvater B, Rossig C, Fröhling S, Hafner S, Simmet T, Åman P, Wardelmann E, Huss S, Hartmann W. Trautmann M, et al. Among authors: wardelmann e. Clin Cancer Res. 2017 Oct 15;23(20):6227-6238. doi: 10.1158/1078-0432.CCR-17-0130. Epub 2017 Jun 21. Clin Cancer Res. 2017. PMID: 28637688
340 results