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Page 1
Sequential C-H Arylation and Enantioselective Hydrogenation Enables Ideal Asymmetric Entry to the Indenopiperidine Core of an 11β-HSD-1 Inhibitor.
Wei X, Qu B, Zeng X, Savoie J, Fandrick KR, Desrosiers JN, Tcyrulnikov S, Marsini MA, Buono FG, Li Z, Yang BS, Tang W, Haddad N, Gutierrez O, Wang J, Lee H, Ma S, Campbell S, Lorenz JC, Eckhardt M, Himmelsbach F, Peters S, Patel ND, Tan Z, Yee NK, Song JJ, Roschangar F, Kozlowski MC, Senanayake CH. Wei X, et al. Among authors: savoie j. J Am Chem Soc. 2016 Nov 30;138(47):15473-15481. doi: 10.1021/jacs.6b09764. Epub 2016 Nov 17. J Am Chem Soc. 2016. PMID: 27794616 Free PMC article.
A general and special catalyst for Suzuki-Miyaura coupling processes.
Tang W, Capacci AG, Wei X, Li W, White A, Patel ND, Savoie J, Gao JJ, Rodriguez S, Qu B, Haddad N, Lu BZ, Krishnamurthy D, Yee NK, Senanayake CH. Tang W, et al. Among authors: savoie j. Angew Chem Int Ed Engl. 2010 Aug 9;49(34):5879-83. doi: 10.1002/anie.201002404. Angew Chem Int Ed Engl. 2010. PMID: 20632427 No abstract available.
Diastereoselective Synthesis of α-Quaternary Aziridine-2-carboxylates via Aza-Corey-Chaykovsky Aziridination of N-tert-Butanesulfinyl Ketimino Esters.
Marsini MA, Reeves JT, Desrosiers JN, Herbage MA, Savoie J, Li Z, Fandrick KR, Sader CA, McKibben B, Gao DA, Cui J, Gonnella NC, Lee H, Wei X, Roschangar F, Lu BZ, Senanayake CH. Marsini MA, et al. Among authors: savoie j. Org Lett. 2015 Nov 20;17(22):5614-7. doi: 10.1021/acs.orglett.5b02838. Epub 2015 Nov 11. Org Lett. 2015. PMID: 26558319
Synthesis of Enantioenriched 2-Alkyl Piperidine Derivatives through Asymmetric Reduction of Pyridinium Salts.
Qu B, Mangunuru HP, Wei X, Fandrick KR, Desrosiers JN, Sieber JD, Kurouski D, Haddad N, Samankumara LP, Lee H, Savoie J, Ma S, Grinberg N, Sarvestani M, Yee NK, Song JJ, Senanayake CH. Qu B, et al. Among authors: savoie j. Org Lett. 2016 Oct 7;18(19):4920-4923. doi: 10.1021/acs.orglett.6b02401. Epub 2016 Sep 23. Org Lett. 2016. PMID: 27661252 Free PMC article.
239 results