Ohta A - Search Results

1

Germinal Center Hypoxia Potentiates Immunoglobulin Class Switch Recombination.

Abbott RK, Thayer M, Labuda J, Silva M, Philbrook P, Cain DW, Kojima H, Hatfield S, Sethumadhavan S, Ohta A, Reinherz EL, Kelsoe G, Sitkovsky M. Abbott RK, et al. Among authors: ohta a. J Immunol. 2016 Nov 15;197(10):4014-4020. doi: 10.4049/jimmunol.1601401. Epub 2016 Oct 19. J Immunol. 2016. PMID: 27798169 Free PMC article.

2

Cutting edge: hypoxia-inducible factor 1alpha and its activation-inducible short isoform I.1 negatively regulate functions of CD4+ and CD8+ T lymphocytes.

Lukashev D, Klebanov B, Kojima H, Grinberg A, Ohta A, Berenfeld L, Wenger RH, Ohta A, Sitkovsky M. Lukashev D, et al. Among authors: ohta a. J Immunol. 2006 Oct 15;177(8):4962-5. doi: 10.4049/jimmunol.177.8.4962. J Immunol. 2006. PMID: 17015677

3

The GS Protein-coupled A2a Adenosine Receptor Controls T Cell Help in the Germinal Center.

Abbott RK, Silva M, Labuda J, Thayer M, Cain DW, Philbrook P, Sethumadhavan S, Hatfield S, Ohta A, Sitkovsky M. Abbott RK, et al. Among authors: ohta a. J Biol Chem. 2017 Jan 27;292(4):1211-1217. doi: 10.1074/jbc.C116.764043. Epub 2016 Dec 14. J Biol Chem. 2017. PMID: 27974461 Free PMC article.

4

Hypoxia and hypoxia-inducible factor (HIF) downregulate antigen-presenting MHC class I molecules limiting tumor cell recognition by T cells.

Sethumadhavan S, Silva M, Philbrook P, Nguyen T, Hatfield SM, Ohta A, Sitkovsky MV. Sethumadhavan S, et al. Among authors: ohta a. PLoS One. 2017 Nov 20;12(11):e0187314. doi: 10.1371/journal.pone.0187314. eCollection 2017. PLoS One. 2017. PMID: 29155844 Free PMC article.

5

A_2A Adenosine Receptor Gene Deletion or Synthetic A_2A Antagonist Liberate Tumor-Reactive CD8⁺ T Cells from Tumor-Induced Immunosuppression.

Kjaergaard J, Hatfield S, Jones G, Ohta A, Sitkovsky M. Kjaergaard J, et al. Among authors: ohta a. J Immunol. 2018 Jul 15;201(2):782-791. doi: 10.4049/jimmunol.1700850. Epub 2018 May 25. J Immunol. 2018. PMID: 29802128 Free PMC article.

6

The 'danger' sensors that STOP the immune response: the A2 adenosine receptors?

Sitkovsky MV, Ohta A. Sitkovsky MV, et al. Among authors: ohta a. Trends Immunol. 2005 Jun;26(6):299-304. doi: 10.1016/j.it.2005.04.004. Trends Immunol. 2005. PMID: 15922945

7

1,3,7-trimethylxanthine (caffeine) may exacerbate acute inflammatory liver injury by weakening the physiological immunosuppressive mechanism.

Ohta A, Lukashev D, Jackson EK, Fredholm BB, Sitkovsky M. Ohta A, et al. J Immunol. 2007 Dec 1;179(11):7431-8. doi: 10.4049/jimmunol.179.11.7431. J Immunol. 2007. PMID: 18025187

8

A2A adenosine receptor may allow expansion of T cells lacking effector functions in extracellular adenosine-rich microenvironments.

Ohta A, Ohta A, Madasu M, Kini R, Subramanian M, Goel N, Sitkovsky M. Ohta A, et al. J Immunol. 2009 Nov 1;183(9):5487-93. doi: 10.4049/jimmunol.0901247. J Immunol. 2009. PMID: 19843934

9

A2B adenosine receptor blockade enhances macrophage-mediated bacterial phagocytosis and improves polymicrobial sepsis survival in mice.

Belikoff BG, Hatfield S, Georgiev P, Ohta A, Lukashev D, Buras JA, Remick DG, Sitkovsky M. Belikoff BG, et al. Among authors: ohta a. J Immunol. 2011 Feb 15;186(4):2444-53. doi: 10.4049/jimmunol.1001567. Epub 2011 Jan 17. J Immunol. 2011. PMID: 21242513 Free PMC article.

10

Genetic deletion of the HIF-1α isoform I.1 in T cells enhances antibacterial immunity and improves survival in a murine peritonitis model.

Georgiev P, Belikoff BG, Hatfield S, Ohta A, Sitkovsky MV, Lukashev D. Georgiev P, et al. Among authors: ohta a. Eur J Immunol. 2013 Mar;43(3):655-66. doi: 10.1002/eji.201242765. Epub 2013 Jan 31. Eur J Immunol. 2013. PMID: 23208786 Free PMC article.

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