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Phosphodiesterase 2 Protects Against Catecholamine-Induced Arrhythmia and Preserves Contractile Function After Myocardial Infarction.
Vettel C, Lindner M, Dewenter M, Lorenz K, Schanbacher C, Riedel M, Lämmle S, Meinecke S, Mason FE, Sossalla S, Geerts A, Hoffmann M, Wunder F, Brunner FJ, Wieland T, Mehel H, Karam S, Lechêne P, Leroy J, Vandecasteele G, Wagner M, Fischmeister R, El-Armouche A. Vettel C, et al. Among authors: fischmeister r. Circ Res. 2017 Jan 6;120(1):120-132. doi: 10.1161/CIRCRESAHA.116.310069. Epub 2016 Oct 31. Circ Res. 2017. PMID: 27799254
cGMP-stimulated cyclic nucleotide phosphodiesterase regulates the basal calcium current in human atrial myocytes.
Rivet-Bastide M, Vandecasteele G, Hatem S, Verde I, Bénardeau A, Mercadier JJ, Fischmeister R. Rivet-Bastide M, et al. Among authors: fischmeister r. J Clin Invest. 1997 Jun 1;99(11):2710-8. doi: 10.1172/JCI119460. J Clin Invest. 1997. PMID: 9169501 Free PMC article.
Recently, EHNA was shown to block the activity of purified soluble cGMPstimulated phosphodiesterase (PDE2) from frog, human, and porcine heart with an apparent Ki value of approximately 1 microM and with negligible effects on Ca2+/calmodulin PDE (PDE1), cGMP-inhibited PDE (PDE3), …
Recently, EHNA was shown to block the activity of purified soluble cGMPstimulated phosphodiesterase (PDE2) from frog, human, and porcine hea …
180 results