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Akt and SHP-1 are DC-intrinsic checkpoints for tumor immunity.
Carmi Y, Prestwood TR, Spitzer MH, Linde IL, Chabon J, Reticker-Flynn NE, Bhattacharya N, Zhang H, Zhang X, Basto PA, Burt BM, Alonso MN, Engleman EG. Carmi Y, et al. Among authors: spitzer mh. JCI Insight. 2016 Nov 3;1(18):e89020. doi: 10.1172/jci.insight.89020. JCI Insight. 2016. PMID: 27812544 Free PMC article.
Allogeneic IgG combined with dendritic cell stimuli induce antitumour T-cell immunity.
Carmi Y, Spitzer MH, Linde IL, Burt BM, Prestwood TR, Perlman N, Davidson MG, Kenkel JA, Segal E, Pusapati GV, Bhattacharya N, Engleman EG. Carmi Y, et al. Among authors: spitzer mh. Nature. 2015 May 7;521(7550):99-104. doi: 10.1038/nature14424. Epub 2015 Apr 29. Nature. 2015. PMID: 25924063 Free PMC article.
Systemic Immunity Is Required for Effective Cancer Immunotherapy.
Spitzer MH, Carmi Y, Reticker-Flynn NE, Kwek SS, Madhireddy D, Martins MM, Gherardini PF, Prestwood TR, Chabon J, Bendall SC, Fong L, Nolan GP, Engleman EG. Spitzer MH, et al. Cell. 2017 Jan 26;168(3):487-502.e15. doi: 10.1016/j.cell.2016.12.022. Epub 2017 Jan 19. Cell. 2017. PMID: 28111070 Free PMC article.
Lymph node colonization induces tumor-immune tolerance to promote distant metastasis.
Reticker-Flynn NE, Zhang W, Belk JA, Basto PA, Escalante NK, Pilarowski GOW, Bejnood A, Martins MM, Kenkel JA, Linde IL, Bagchi S, Yuan R, Chang S, Spitzer MH, Carmi Y, Cheng J, Tolentino LL, Choi O, Wu N, Kong CS, Gentles AJ, Sunwoo JB, Satpathy AT, Plevritis SK, Engleman EG. Reticker-Flynn NE, et al. Among authors: spitzer mh. Cell. 2022 May 26;185(11):1924-1942.e23. doi: 10.1016/j.cell.2022.04.019. Epub 2022 May 6. Cell. 2022. PMID: 35525247 Free PMC article.
Systemic immunity in cancer.
Hiam-Galvez KJ, Allen BM, Spitzer MH. Hiam-Galvez KJ, et al. Among authors: spitzer mh. Nat Rev Cancer. 2021 Jun;21(6):345-359. doi: 10.1038/s41568-021-00347-z. Epub 2021 Apr 9. Nat Rev Cancer. 2021. PMID: 33837297 Free PMC article. Review.
79 results