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614 results

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Page 1
Inhibition of citrate cotransporter Slc13a5/mINDY by RNAi improves hepatic insulin sensitivity and prevents diet-induced non-alcoholic fatty liver disease in mice.
Brachs S, Winkel AF, Tang H, Birkenfeld AL, Brunner B, Jahn-Hofmann K, Margerie D, Ruetten H, Schmoll D, Spranger J. Brachs S, et al. Among authors: spranger j. Mol Metab. 2016 Aug 13;5(11):1072-1082. doi: 10.1016/j.molmet.2016.08.004. eCollection 2016 Nov. Mol Metab. 2016. PMID: 27818933 Free PMC article.
Physiological modulation of circulating FGF21: relevance of free fatty acids and insulin.
Mai K, Bobbert T, Groth C, Assmann A, Meinus S, Kraatz J, Andres J, Arafat AM, Pfeiffer AF, Möhlig M, Spranger J. Mai K, et al. Among authors: spranger j. Am J Physiol Endocrinol Metab. 2010 Jul;299(1):E126-30. doi: 10.1152/ajpendo.00020.2010. Epub 2010 Apr 27. Am J Physiol Endocrinol Metab. 2010. PMID: 20424140 Free article. Clinical Trial.
Deletion of the mammalian INDY homolog mimics aspects of dietary restriction and protects against adiposity and insulin resistance in mice.
Birkenfeld AL, Lee HY, Guebre-Egziabher F, Alves TC, Jurczak MJ, Jornayvaz FR, Zhang D, Hsiao JJ, Martin-Montalvo A, Fischer-Rosinsky A, Spranger J, Pfeiffer AF, Jordan J, Fromm MF, König J, Lieske S, Carmean CM, Frederick DW, Weismann D, Knauf F, Irusta PM, De Cabo R, Helfand SL, Samuel VT, Shulman GI. Birkenfeld AL, et al. Among authors: spranger j. Cell Metab. 2011 Aug 3;14(2):184-95. doi: 10.1016/j.cmet.2011.06.009. Cell Metab. 2011. PMID: 21803289 Free PMC article.
Weight Loss Partially Restores Glucose-Driven Betatrophin Response in Humans.
Maurer L, Brachs S, Decker AM, Brachs M, Leupelt V, Jumpertz von Schwartzenberg R, Ernert A, Bobbert T, Krude H, Spranger J, Mai K. Maurer L, et al. Among authors: spranger j. J Clin Endocrinol Metab. 2016 Nov;101(11):4014-4020. doi: 10.1210/jc.2016-1788. Epub 2016 Jul 26. J Clin Endocrinol Metab. 2016. PMID: 27459526
Renal function is independently associated with circulating betatrophin.
Maurer L, Schwarz F, Fischer-Rosinsky A, Schlueter N, Brachs S, Möhlig M, Pfeiffer A, Mai K, Spranger J, Bobbert T. Maurer L, et al. Among authors: spranger j. PLoS One. 2017 Mar 3;12(3):e0173197. doi: 10.1371/journal.pone.0173197. eCollection 2017. PLoS One. 2017. PMID: 28257453 Free PMC article.
ANGPTL8 (Betatrophin) is Expressed in Visceral Adipose Tissue and Relates to Human Hepatic Steatosis in Two Independent Clinical Collectives.
von Loeffelholz C, Pfeiffer AFH, Lock JF, Lieske S, Döcke S, Murahovschi V, Kriebel J, de Las Heras Gala T, Grallert H, Rudovich N, Stockmann M, Spranger J, Jahreis G, Bornstein SR, Lau G, Xu A, Schulz-Menger J, Exner L, Haufe S, Jordan J, Engeli S, Birkenfeld AL. von Loeffelholz C, et al. Among authors: spranger j. Horm Metab Res. 2017 May;49(5):343-349. doi: 10.1055/s-0043-102950. Epub 2017 Mar 28. Horm Metab Res. 2017. PMID: 28351093 Clinical Trial.
614 results