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Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism.
Kato AS, Burris KD, Gardinier KM, Gernert DL, Porter WJ, Reel J, Ding C, Tu Y, Schober DA, Lee MR, Heinz BA, Fitch TE, Gleason SD, Catlow JT, Yu H, Fitzjohn SM, Pasqui F, Wang H, Qian Y, Sher E, Zwart R, Wafford KA, Rasmussen K, Ornstein PL, Isaac JT, Nisenbaum ES, Bredt DS, Witkin JM. Kato AS, et al. Among authors: lee mr. Nat Med. 2016 Dec;22(12):1496-1501. doi: 10.1038/nm.4221. Epub 2016 Nov 7. Nat Med. 2016. PMID: 27820603
A randomized, double-blind, placebo-controlled study of a GHSR blocker in people with alcohol use disorder.
Faulkner ML, Farokhnia M, Lee MR, Farinelli L, Browning BD, Abshire K, Daurio AM, Munjal V, Deschaine SL, Boukabara SR, Fortney C, Sherman G, Schwandt M, Akhlaghi F, Momenan R, Ross TJ, Persky S, Leggio L. Faulkner ML, et al. Among authors: lee mr. JCI Insight. 2024 Dec 20;9(24):e182331. doi: 10.1172/jci.insight.182331. JCI Insight. 2024. PMID: 39704175 Free PMC article. Clinical Trial.
ATR inhibition promotes synergistic antitumor effect in platinum-resistant pancreatic cancer.
Chun JW, Shon HW, Gong JE, Lee MR, Lee YS, Kim SJ, Kang S, Kim S, Lee KY, Woo SM, Cho IR, Paik WH, Lee WJ, Kong SY, Ryu JK, Kim YT, Lee SH, Kim YH. Chun JW, et al. Among authors: lee mr. Biochim Biophys Acta Mol Basis Dis. 2024 Dec 15;1871(3):167625. doi: 10.1016/j.bbadis.2024.167625. Online ahead of print. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 39689762 Free article.
1,296 results