Yu H - Search Results

1

Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism.

Kato AS, Burris KD, Gardinier KM, Gernert DL, Porter WJ, Reel J, Ding C, Tu Y, Schober DA, Lee MR, Heinz BA, Fitch TE, Gleason SD, Catlow JT, Yu H, Fitzjohn SM, Pasqui F, Wang H, Qian Y, Sher E, Zwart R, Wafford KA, Rasmussen K, Ornstein PL, Isaac JT, Nisenbaum ES, Bredt DS, Witkin JM. Kato AS, et al. Among authors: yu h. Nat Med. 2016 Dec;22(12):1496-1501. doi: 10.1038/nm.4221. Epub 2016 Nov 7. Nat Med. 2016. PMID: 27820603

2

Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins.

Kato AS, Gill MB, Ho MT, Yu H, Tu Y, Siuda ER, Wang H, Qian YW, Nisenbaum ES, Tomita S, Bredt DS. Kato AS, et al. Among authors: yu h. Neuron. 2010 Dec 22;68(6):1082-96. doi: 10.1016/j.neuron.2010.11.026. Neuron. 2010. PMID: 21172611 Free PMC article.

3

Transmembrane AMPA receptor regulatory proteins and cornichon-2 allosterically regulate AMPA receptor antagonists and potentiators.

Schober DA, Gill MB, Yu H, Gernert DL, Jeffries MW, Ornstein PL, Kato AS, Felder CC, Bredt DS. Schober DA, et al. Among authors: yu h. J Biol Chem. 2011 Apr 15;286(15):13134-42. doi: 10.1074/jbc.M110.212522. Epub 2011 Feb 22. J Biol Chem. 2011. PMID: 21343286 Free PMC article.

4

Discovery of the First α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent upon Transmembrane AMPA Receptor Regulatory Protein (TARP) γ-8.

Gardinier KM, Gernert DL, Porter WJ, Reel JK, Ornstein PL, Spinazze P, Stevens FC, Hahn P, Hollinshead SP, Mayhugh D, Schkeryantz J, Khilevich A, De Frutos O, Gleason SD, Kato AS, Luffer-Atlas D, Desai PV, Swanson S, Burris KD, Ding C, Heinz BA, Need AB, Barth VN, Stephenson GA, Diseroad BA, Woods TA, Yu H, Bredt D, Witkin JM. Gardinier KM, et al. Among authors: yu h. J Med Chem. 2016 May 26;59(10):4753-68. doi: 10.1021/acs.jmedchem.6b00125. Epub 2016 Apr 29. J Med Chem. 2016. PMID: 27067148

5

New transmembrane AMPA receptor regulatory protein isoform, gamma-7, differentially regulates AMPA receptors.

Kato AS, Zhou W, Milstein AD, Knierman MD, Siuda ER, Dotzlaf JE, Yu H, Hale JE, Nisenbaum ES, Nicoll RA, Bredt DS. Kato AS, et al. Among authors: yu h. J Neurosci. 2007 May 2;27(18):4969-77. doi: 10.1523/JNEUROSCI.5561-06.2007. J Neurosci. 2007. PMID: 17475805 Free PMC article.

6

TARPs differentially decorate AMPA receptors to specify neuropharmacology.

Kato AS, Gill MB, Yu H, Nisenbaum ES, Bredt DS. Kato AS, et al. Among authors: yu h. Trends Neurosci. 2010 May;33(5):241-8. doi: 10.1016/j.tins.2010.02.004. Epub 2010 Mar 8. Trends Neurosci. 2010. PMID: 20219255 Review.

7

Cornichon-2 modulates AMPA receptor-transmembrane AMPA receptor regulatory protein assembly to dictate gating and pharmacology.

Gill MB, Kato AS, Roberts MF, Yu H, Wang H, Tomita S, Bredt DS. Gill MB, et al. Among authors: yu h. J Neurosci. 2011 May 4;31(18):6928-38. doi: 10.1523/JNEUROSCI.6271-10.2011. J Neurosci. 2011. PMID: 21543622 Free PMC article.

8

A single residue contributes sensitivity to allosteric modulation of AMPA receptors by LY395153.

Quirk JC, Linden AM, Strakhova M, Yu H, Skolnick P, Nisenbaum ES. Quirk JC, et al. Among authors: yu h. Eur J Pharmacol. 2002 Nov 15;454(2-3):125-9. doi: 10.1016/s0014-2999(02)02491-3. Eur J Pharmacol. 2002. PMID: 12421639

9

AMPA receptor function is altered in GLUR2-deficient mice.

Harvey SC, Köster A, Yu H, Skolnick P, Baumbarger P, Nisenbaum ES. Harvey SC, et al. Among authors: yu h. J Mol Neurosci. 2001 Aug;17(1):35-43. doi: 10.1385/JMN:17:1:35. J Mol Neurosci. 2001. PMID: 11665861

10

α7 nicotinic acetylcholine receptor upregulation by anti-apoptotic Bcl-2 proteins.

Dawe GB, Yu H, Gu S, Blackler AN, Matta JA, Siuda ER, Rex EB, Bredt DS. Dawe GB, et al. Among authors: yu h. Nat Commun. 2019 Jun 21;10(1):2746. doi: 10.1038/s41467-019-10723-x. Nat Commun. 2019. PMID: 31227712 Free PMC article.

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