Bjornsti MA - Search Results

1

Molecular Mechanism of DNA Topoisomerase I-Dependent rDNA Silencing: Sir2p Recruitment at Ribosomal Genes.

D'Alfonso A, Di Felice F, Carlini V, Wright CM, Hertz MI, Bjornsti MA, Camilloni G. D'Alfonso A, et al. Among authors: bjornsti ma. J Mol Biol. 2016 Dec 4;428(24 Pt B):4905-4916. doi: 10.1016/j.jmb.2016.10.032. Epub 2016 Nov 5. J Mol Biol. 2016. PMID: 27825925

2

DNA topoisomerase I domain interactions impact enzyme activity and sensitivity to camptothecin.

Wright CM, van der Merwe M, DeBrot AH, Bjornsti MA. Wright CM, et al. Among authors: bjornsti ma. J Biol Chem. 2015 May 8;290(19):12068-78. doi: 10.1074/jbc.M114.635078. Epub 2015 Mar 20. J Biol Chem. 2015. PMID: 25795777 Free PMC article.

3

Mutation of a conserved active site residue converts tyrosyl-DNA phosphodiesterase I into a DNA topoisomerase I-dependent poison.

He X, van Waardenburg RCAM, Babaoglu K, Price AC, Nitiss KC, Nitiss JL, Bjornsti MA, White SW. He X, et al. Among authors: bjornsti ma. J Mol Biol. 2007 Sep 28;372(4):1070-1081. doi: 10.1016/j.jmb.2007.07.055. Epub 2007 Aug 2. J Mol Biol. 2007. PMID: 17707402

4

UBC9 Mutant Reveals the Impact of Protein Dynamics on Substrate Selectivity and SUMO Chain Linkages.

Wright CM, Whitaker RH, Onuiri JE, Blackburn T, McGarity S, Bjornsti MA, Placzek WJ. Wright CM, et al. Among authors: bjornsti ma. Biochemistry. 2019 Feb 12;58(6):621-632. doi: 10.1021/acs.biochem.8b01045. Epub 2019 Jan 10. Biochemistry. 2019. PMID: 30574775 Free PMC article.

5

DNA topoisomerase-targeting chemotherapeutics: what's new?

Cuya SM, Bjornsti MA, van Waardenburg RCAM. Cuya SM, et al. Among authors: bjornsti ma. Cancer Chemother Pharmacol. 2017 Jul;80(1):1-14. doi: 10.1007/s00280-017-3334-5. Epub 2017 May 20. Cancer Chemother Pharmacol. 2017. PMID: 28528358 Free PMC article. Review.

6

Overexpression and purification of DNA topoisomerase I from yeast.

Bjornsti MA, Fertala J. Bjornsti MA, et al. Methods Mol Biol. 1999;94:179-86. doi: 10.1385/1-59259-259-7:179. Methods Mol Biol. 1999. PMID: 12844874 No abstract available.

7

Domain interactions affecting human DNA topoisomerase I catalysis and camptothecin sensitivity.

Fiorani P, Amatruda JF, Silvestri A, Butler RH, Bjornsti MA, Benedetti P. Fiorani P, et al. Among authors: bjornsti ma. Mol Pharmacol. 1999 Dec;56(6):1105-15. doi: 10.1124/mol.56.6.1105. Mol Pharmacol. 1999. PMID: 10570037

8

Mutation of Gly721 alters DNA topoisomerase I active site architecture and sensitivity to camptothecin.

van der Merwe M, Bjornsti MA. van der Merwe M, et al. Among authors: bjornsti ma. J Biol Chem. 2008 Feb 8;283(6):3305-3315. doi: 10.1074/jbc.M705781200. Epub 2007 Dec 4. J Biol Chem. 2008. PMID: 18056711 Free PMC article.

9

Studying DNA topoisomerase I-targeted drugs in the yeast. Saccharomyces cerevisiae.

Woo MH, Vance JR, Bjornsti MA. Woo MH, et al. Among authors: bjornsti ma. Methods Mol Biol. 2001;95:303-13. doi: 10.1385/1-59259-057-8:303. Methods Mol Biol. 2001. PMID: 11089242 No abstract available.

10

Introduction to DNA topoisomerases.

Bjornsti MA, Osheroff N. Bjornsti MA, et al. Methods Mol Biol. 1999;94:1-8. doi: 10.1385/1-59259-259-7:1. Methods Mol Biol. 1999. PMID: 12844856 Review. No abstract available.

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