Roepe PD - Search Results

1

Evolution of Fitness Cost-Neutral Mutant PfCRT Conferring P. falciparum 4-Aminoquinoline Drug Resistance Is Accompanied by Altered Parasite Metabolism and Digestive Vacuole Physiology.

Gabryszewski SJ, Dhingra SK, Combrinck JM, Lewis IA, Callaghan PS, Hassett MR, Siriwardana A, Henrich PP, Lee AH, Gnädig NF, Musset L, Llinás M, Egan TJ, Roepe PD, Fidock DA. Gabryszewski SJ, et al. Among authors: roepe pd. PLoS Pathog. 2016 Nov 10;12(11):e1005976. doi: 10.1371/journal.ppat.1005976. eCollection 2016 Nov. PLoS Pathog. 2016. PMID: 27832198 Free PMC article.

2

Are ion-exchange processes central to understanding drug-resistance phenomena?

Roepe PD, Martiney JA. Roepe PD, et al. Trends Pharmacol Sci. 1999 Feb;20(2):62-5. doi: 10.1016/s0165-6147(98)01282-6. Trends Pharmacol Sci. 1999. PMID: 10101966 Free article. Review.

3

Digestive vacuolar pH of intact intraerythrocytic P. falciparum either sensitive or resistant to chloroquine.

Dzekunov SM, Ursos LM, Roepe PD. Dzekunov SM, et al. Among authors: roepe pd. Mol Biochem Parasitol. 2000 Sep;110(1):107-24. doi: 10.1016/s0166-6851(00)00261-9. Mol Biochem Parasitol. 2000. PMID: 10989149

4

The effects of chloroquine and verapamil on digestive vacuolar pH of P. falciparum either sensitive or resistant to chloroquine.

Ursos LM, Dzekunov SM, Roepe PD. Ursos LM, et al. Among authors: roepe pd. Mol Biochem Parasitol. 2000 Sep;110(1):125-34. doi: 10.1016/s0166-6851(00)00262-0. Mol Biochem Parasitol. 2000. PMID: 10989150

5

Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance.

Fidock DA, Nomura T, Talley AK, Cooper RA, Dzekunov SM, Ferdig MT, Ursos LM, Sidhu AB, Naudé B, Deitsch KW, Su XZ, Wootton JC, Roepe PD, Wellems TE. Fidock DA, et al. Among authors: roepe pd. Mol Cell. 2000 Oct;6(4):861-71. doi: 10.1016/s1097-2765(05)00077-8. Mol Cell. 2000. PMID: 11090624 Free PMC article.

6

Evolution of a unique Plasmodium falciparum chloroquine-resistance phenotype in association with pfcrt polymorphism in Papua New Guinea and South America.

Mehlotra RK, Fujioka H, Roepe PD, Janneh O, Ursos LM, Jacobs-Lorena V, McNamara DT, Bockarie MJ, Kazura JW, Kyle DE, Fidock DA, Zimmerman PA. Mehlotra RK, et al. Among authors: roepe pd. Proc Natl Acad Sci U S A. 2001 Oct 23;98(22):12689-94. doi: 10.1073/pnas.221440898. Proc Natl Acad Sci U S A. 2001. PMID: 11675500 Free PMC article.

7

Alternative mutations at position 76 of the vacuolar transmembrane protein PfCRT are associated with chloroquine resistance and unique stereospecific quinine and quinidine responses in Plasmodium falciparum.

Cooper RA, Ferdig MT, Su XZ, Ursos LM, Mu J, Nomura T, Fujioka H, Fidock DA, Roepe PD, Wellems TE. Cooper RA, et al. Among authors: roepe pd. Mol Pharmacol. 2002 Jan;61(1):35-42. doi: 10.1124/mol.61.1.35. Mol Pharmacol. 2002. PMID: 11752204

8

Chloroquine resistance in the malarial parasite, Plasmodium falciparum.

Ursos LM, Roepe PD. Ursos LM, et al. Among authors: roepe pd. Med Res Rev. 2002 Sep;22(5):465-91. doi: 10.1002/med.10016. Med Res Rev. 2002. PMID: 12210555 Review.

9

A novel transporter, Pfcrt, confers antimalarial drug resistance.

Howard EM, Zhang H, Roepe PD. Howard EM, et al. Among authors: roepe pd. J Membr Biol. 2002 Nov 1;190(1):1-8. doi: 10.1007/s00232-002-1019-3. J Membr Biol. 2002. PMID: 12422267 Review.

10

Chloroquine resistance modulated in vitro by expression levels of the Plasmodium falciparum chloroquine resistance transporter.

Waller KL, Muhle RA, Ursos LM, Horrocks P, Verdier-Pinard D, Sidhu AB, Fujioka H, Roepe PD, Fidock DA. Waller KL, et al. Among authors: roepe pd. J Biol Chem. 2003 Aug 29;278(35):33593-601. doi: 10.1074/jbc.M302215200. Epub 2003 Jun 17. J Biol Chem. 2003. PMID: 12813054 Free article.

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