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Neuron-Targeted Caveolin-1 Improves Molecular Signaling, Plasticity, and Behavior Dependent on the Hippocampus in Adult and Aged Mice.
Mandyam CD, Schilling JM, Cui W, Egawa J, Niesman IR, Kellerhals SE, Staples MC, Busija AR, Risbrough VB, Posadas E, Grogman GC, Chang JW, Roth DM, Patel PM, Patel HH, Head BP. Mandyam CD, et al. Among authors: egawa j. Biol Psychiatry. 2017 Jan 15;81(2):101-110. doi: 10.1016/j.biopsych.2015.09.020. Epub 2015 Oct 8. Biol Psychiatry. 2017. PMID: 26592463 Free PMC article.
Neuron-specific caveolin-1 overexpression improves motor function and preserves memory in mice subjected to brain trauma.
Egawa J, Schilling JM, Cui W, Posadas E, Sawada A, Alas B, Zemljic-Harpf AE, Fannon-Pavlich MJ, Mandyam CD, Roth DM, Patel HH, Patel PM, Head BP. Egawa J, et al. FASEB J. 2017 Aug;31(8):3403-3411. doi: 10.1096/fj.201601288RRR. Epub 2017 Apr 27. FASEB J. 2017. PMID: 28450301 Free PMC article.
Our findings demonstrate that neuron-targeted Cav-1 can be used as a novel therapeutic strategy to restore brain function and prevent trauma-associated maladaptive plasticity.-Egawa, J., Schilling, J. M., Cui, W., Posadas, E., Sawada, A., Alas, B., Zemljic-Ha …
Our findings demonstrate that neuron-targeted Cav-1 can be used as a novel therapeutic strategy to restore brain function and prevent trauma …
Neuron-targeted caveolin-1 improves neuromuscular function and extends survival in SOD1G93A mice.
Sawada A, Wang S, Jian M, Leem J, Wackerbarth J, Egawa J, Schilling JM, Platoshyn O, Zemljic-Harpf A, Roth DM, Patel HH, Patel PM, Marsala M, Head BP. Sawada A, et al. Among authors: egawa j. FASEB J. 2019 Jun;33(6):7545-7554. doi: 10.1096/fj.201802652RR. Epub 2019 Mar 20. FASEB J. 2019. PMID: 30894019 Free PMC article.
These findings demonstrate that SynCav1 delays disease progression in a mouse model of ALS, potentially by preserving or restoring NTR expression and localization to MLRs.-Sawada, A., Wang, S., Jian, M., Leem, J., Wackerbarth, J., Egawa, J., Schilling, …
These findings demonstrate that SynCav1 delays disease progression in a mouse model of ALS, potentially by preserving or restoring NTR expre …
Inhibition of RhoA reduces propofol-mediated growth cone collapse, axonal transport impairment, loss of synaptic connectivity, and behavioural deficits.
Pearn ML, Schilling JM, Jian M, Egawa J, Wu C, Mandyam CD, Fannon-Pavlich MJ, Nguyen U, Bertoglio J, Kodama M, Mahata SK, DerMardirossian C, Lemkuil BP, Han R, Mobley WC, Patel HH, Patel PM, Head BP. Pearn ML, et al. Among authors: egawa j. Br J Anaesth. 2018 Apr;120(4):745-760. doi: 10.1016/j.bja.2017.12.033. Epub 2018 Feb 15. Br J Anaesth. 2018. PMID: 29576115 Free PMC article.
139 results