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TTI-621 (SIRPαFc): A CD47-Blocking Innate Immune Checkpoint Inhibitor with Broad Antitumor Activity and Minimal Erythrocyte Binding.
Petrova PS, Viller NN, Wong M, Pang X, Lin GH, Dodge K, Chai V, Chen H, Lee V, House V, Vigo NT, Jin D, Mutukura T, Charbonneau M, Truong T, Viau S, Johnson LD, Linderoth E, Sievers EL, Maleki Vareki S, Figueredo R, Pampillo M, Koropatnick J, Trudel S, Mbong N, Jin L, Wang JC, Uger RA. Petrova PS, et al. Among authors: jin d, jin l. Clin Cancer Res. 2017 Feb 15;23(4):1068-1079. doi: 10.1158/1078-0432.CCR-16-1700. Epub 2016 Nov 17. Clin Cancer Res. 2017. PMID: 27856600
Concepts of human leukemic development.
Warner JK, Wang JC, Hope KJ, Jin L, Dick JE. Warner JK, et al. Among authors: jin l. Oncogene. 2004 Sep 20;23(43):7164-77. doi: 10.1038/sj.onc.1207933. Oncogene. 2004. PMID: 15378077 Review.
AGS67E, an Anti-CD37 Monomethyl Auristatin E Antibody-Drug Conjugate as a Potential Therapeutic for B/T-Cell Malignancies and AML: A New Role for CD37 in AML.
Pereira DS, Guevara CI, Jin L, Mbong N, Verlinsky A, Hsu SJ, Aviña H, Karki S, Abad JD, Yang P, Moon SJ, Malik F, Choi MY, An Z, Morrison K, Challita-Eid PM, Doñate F, Joseph IB, Kipps TJ, Dick JE, Stover DR. Pereira DS, et al. Among authors: jin l. Mol Cancer Ther. 2015 Jul;14(7):1650-60. doi: 10.1158/1535-7163.MCT-15-0067. Epub 2015 May 1. Mol Cancer Ther. 2015. PMID: 25934707 Free PMC article.
SIRPαFc treatment targets human acute myeloid leukemia stem cells.
Galkin O, McLeod J, Kennedy JA, Jin L, Mbong N, Wong M, Uger RA, Minden MD, Danska JS, Wang JCY. Galkin O, et al. Among authors: jin l. Haematologica. 2021 Jan 1;106(1):279-283. doi: 10.3324/haematol.2019.245167. Haematologica. 2021. PMID: 32054659 Free PMC article. No abstract available.
CD200 expression marks leukemia stem cells in human AML.
Ho JM, Dobson SM, Voisin V, McLeod J, Kennedy JA, Mitchell A, Jin L, Eppert K, Bader G, Minden MD, Dick JE, Wang JCY. Ho JM, et al. Among authors: jin l. Blood Adv. 2020 Nov 10;4(21):5402-5413. doi: 10.1182/bloodadvances.2020001802. Blood Adv. 2020. PMID: 33147339 Free PMC article.
CC-90009, a novel cereblon E3 ligase modulator, targets acute myeloid leukemia blasts and leukemia stem cells.
Surka C, Jin L, Mbong N, Lu CC, Jang IS, Rychak E, Mendy D, Clayton T, Tindall E, Hsu C, Fontanillo C, Tran E, Contreras A, Ng SWK, Matyskiela M, Wang K, Chamberlain P, Cathers B, Carmichael J, Hansen J, Wang JCY, Minden MD, Fan J, Pierce DW, Pourdehnad M, Rolfe M, Lopez-Girona A, Dick JE, Lu G. Surka C, et al. Among authors: jin l. Blood. 2021 Feb 4;137(5):661-677. doi: 10.1182/blood.2020008676. Blood. 2021. PMID: 33197925 Free PMC article.
Sphingosine-1-phosphate receptor 3 potentiates inflammatory programs in normal and leukemia stem cells to promote differentiation.
Xie SZ, Kaufmann KB, Wang W, Chan-Seng-Yue M, Gan OI, Laurenti E, Garcia-Prat L, Takayanagi SI, Ng SWK, Xu C, Zeng AGX, Jin L, McLeod J, Wagenblast E, Mitchell A, Kennedy JA, Liu Q, Boutzen H, Kleinau M, Jargstorf J, Holmes G, Zhang Y, Voisin V, Bader GD, Wang JCY, Hannun YA, Luberto C, Schroeder T, Minden MD, Dick JE. Xie SZ, et al. Among authors: jin l. Blood Cancer Discov. 2021 Jan 1;2(1):32-53. doi: 10.1158/2643-3230.BCD-20-0155. Epub 2020 Dec 1. Blood Cancer Discov. 2021. PMID: 33458693 Free PMC article.
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[No authors listed] [No authors listed] PMID: 34238756
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