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Propofol inhibits the voltage-gated sodium channel NaChBac at multiple sites.
Wang Y, Yang E, Wells MM, Bondarenko V, Woll K, Carnevale V, Granata D, Klein ML, Eckenhoff RG, Dailey WP, Covarrubias M, Tang P, Xu Y. Wang Y, et al. Among authors: bondarenko v. J Gen Physiol. 2018 Sep 3;150(9):1317-1331. doi: 10.1085/jgp.201811993. Epub 2018 Jul 17. J Gen Physiol. 2018. PMID: 30018039 Free PMC article.
Regulation and drug modulation of a voltage-gated sodium channel: Pivotal role of the S4-S5 linker in activation and slow inactivation.
Xiao J, Bondarenko V, Wang Y, Suma A, Wells M, Chen Q, Tillman T, Luo Y, Yu B, Dailey WP, Eckenhoff R, Tang P, Carnevale V, Klein ML, Xu Y. Xiao J, et al. Among authors: bondarenko v. Proc Natl Acad Sci U S A. 2021 Jul 13;118(28):e2102285118. doi: 10.1073/pnas.2102285118. Proc Natl Acad Sci U S A. 2021. PMID: 34260401 Free PMC article.
776 results