Hartmann RW - Search Results

1

Metal-Free meta-Selective Alkyne Oxyarylation with Pyridine N-Oxides: Rapid Assembly of Metyrapone Analogues.

Chen X, Ruider SA, Hartmann RW, González L, Maulide N. Chen X, et al. Among authors: hartmann rw. Angew Chem Int Ed Engl. 2016 Dec 5;55(49):15424-15428. doi: 10.1002/anie.201607988. Epub 2016 Nov 9. Angew Chem Int Ed Engl. 2016. PMID: 27862782

2

Overcoming the unexpected functional inversion of a PqsR antagonist in Pseudomonas aeruginosa: an in vivo potent antivirulence agent targeting pqs quorum sensing.

Lu C, Maurer CK, Kirsch B, Steinbach A, Hartmann RW. Lu C, et al. Among authors: hartmann rw. Angew Chem Int Ed Engl. 2014 Jan 20;53(4):1109-12. doi: 10.1002/anie.201307547. Epub 2013 Dec 11. Angew Chem Int Ed Engl. 2014. PMID: 24338917

3

Squalenyl Hydrogen Sulfate Nanoparticles for Simultaneous Delivery of Tobramycin and an Alkylquinolone Quorum Sensing Inhibitor Enable the Eradication of P. aeruginosa Biofilm Infections.

Ho DK, Murgia X, De Rossi C, Christmann R, Hüfner de Mello Martins AG, Koch M, Andreas A, Herrmann J, Müller R, Empting M, Hartmann RW, Desmaele D, Loretz B, Couvreur P, Lehr CM. Ho DK, et al. Among authors: hartmann rw. Angew Chem Int Ed Engl. 2020 Jun 22;59(26):10292-10296. doi: 10.1002/anie.202001407. Epub 2020 May 11. Angew Chem Int Ed Engl. 2020. PMID: 32243047 Free PMC article.

4

Substrate-Inspired Fragment Merging and Growing Affords Efficacious LasB Inhibitors.

Kaya C, Walter I, Yahiaoui S, Sikandar A, Alhayek A, Konstantinović J, Kany AM, Haupenthal J, Köhnke J, Hartmann RW, Hirsch AKH. Kaya C, et al. Among authors: hartmann rw. Angew Chem Int Ed Engl. 2022 Jan 26;61(5):e202112295. doi: 10.1002/anie.202112295. Epub 2021 Dec 13. Angew Chem Int Ed Engl. 2022. PMID: 34762767 Free PMC article.

5

Novel imidazol-1-ylmethyl substituted 1,2,5,6-tetrahydropyrrolo[3,2,1-ij]quinolin-4-ones as potent and selective CYP11B1 inhibitors for the treatment of Cushing's syndrome.

Yin L, Lucas S, Maurer F, Kazmaier U, Hu Q, Hartmann RW. Yin L, et al. Among authors: hartmann rw. J Med Chem. 2012 Jul 26;55(14):6629-33. doi: 10.1021/jm3003872. Epub 2012 Jul 12. J Med Chem. 2012. PMID: 22788843

6

Discovery of new 7-substituted-4-imidazolylmethyl coumarins and 4'-substituted-2-imidazolyl acetophenones open analogues as potent and selective inhibitors of steroid-11β-hydroxylase.

Stefanachi A, Hanke N, Pisani L, Leonetti F, Nicolotti O, Catto M, Cellamare S, Hartmann RW, Carotti A. Stefanachi A, et al. Among authors: hartmann rw. Eur J Med Chem. 2015 Jan 7;89:106-14. doi: 10.1016/j.ejmech.2014.10.021. Epub 2014 Oct 13. Eur J Med Chem. 2015. PMID: 25462231 Free article.

7

Identification of 4-(4-nitro-2-phenethoxyphenyl)pyridine as a promising new lead for discovering inhibitors of both human and rat 11β-Hydroxylase.

Hu Q, Kunde J, Hanke N, Hartmann RW. Hu Q, et al. Among authors: hartmann rw. Eur J Med Chem. 2015;96:139-50. doi: 10.1016/j.ejmech.2015.04.013. Epub 2015 Apr 8. Eur J Med Chem. 2015. PMID: 25874338

8

Accelerated skin wound healing by selective 11β-Hydroxylase (CYP11B1) inhibitors.

Emmerich J, van Koppen CJ, Burkhart JL, Engeli RT, Hu Q, Odermatt A, Hartmann RW. Emmerich J, et al. Among authors: hartmann rw. Eur J Med Chem. 2018 Jan 1;143:591-597. doi: 10.1016/j.ejmech.2017.11.018. Epub 2017 Nov 21. Eur J Med Chem. 2018. PMID: 29207342

9

Synthesis and evaluation of (pyridylmethylene)tetrahydronaphthalenes/-indanes and structurally modified derivatives: potent and selective inhibitors of aldosterone synthase.

Ulmschneider S, Müller-Vieira U, Klein CD, Antes I, Lengauer T, Hartmann RW. Ulmschneider S, et al. Among authors: hartmann rw. J Med Chem. 2005 Mar 10;48(5):1563-75. doi: 10.1021/jm0492397. J Med Chem. 2005. PMID: 15743198

10

Synthesis and evaluation of imidazolylmethylenetetrahydronaphthalenes and imidazolylmethyleneindanes: potent inhibitors of aldosterone synthase.

Ulmschneider S, Müller-Vieira U, Mitrenga M, Hartmann RW, Oberwinkler-Marchais S, Klein CD, Bureik M, Bernhardt R, Antes I, Lengauer T. Ulmschneider S, et al. Among authors: hartmann rw. J Med Chem. 2005 Mar 24;48(6):1796-805. doi: 10.1021/jm049600p. J Med Chem. 2005. PMID: 15771425

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