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Secretory products from epicardial adipose tissue from patients with type 2 diabetes impair mitochondrial β-oxidation in cardiomyocytes via activation of the cardiac renin-angiotensin system and induction of miR-208a.
Blumensatt M, Fahlbusch P, Hilgers R, Bekaert M, Herzfeld de Wiza D, Akhyari P, Ruige JB, Ouwens DM. Blumensatt M, et al. Among authors: ouwens dm. Basic Res Cardiol. 2017 Jan;112(1):2. doi: 10.1007/s00395-016-0591-0. Epub 2016 Nov 18. Basic Res Cardiol. 2017. PMID: 27864612
Activin A impairs insulin action in cardiomyocytes via up-regulation of miR-143.
Blumensatt M, Greulich S, Herzfeld de Wiza D, Mueller H, Maxhera B, Rabelink MJ, Hoeben RC, Akhyari P, Al-Hasani H, Ruige JB, Ouwens DM. Blumensatt M, et al. Among authors: ouwens dm. Cardiovasc Res. 2013 Nov 1;100(2):201-10. doi: 10.1093/cvr/cvt173. Epub 2013 Jun 28. Cardiovasc Res. 2013. PMID: 23812417
Activin A is associated with impaired myocardial glucose metabolism and left ventricular remodeling in patients with uncomplicated type 2 diabetes.
Chen WJ, Greulich S, van der Meer RW, Rijzewijk LJ, Lamb HJ, de Roos A, Smit JW, Romijn JA, Ruige JB, Lammertsma AA, Lubberink M, Diamant M, Ouwens DM. Chen WJ, et al. Among authors: ouwens dm. Cardiovasc Diabetol. 2013 Oct 17;12:150. doi: 10.1186/1475-2840-12-150. Cardiovasc Diabetol. 2013. PMID: 24134550 Free PMC article. Clinical Trial.
Reduced expression of chemerin in visceral adipose tissue associates with hepatic steatosis in patients with obesity.
Bekaert M, Ouwens DM, Hörbelt T, Van de Velde F, Fahlbusch P, Herzfeld de Wiza D, Van Nieuwenhove Y, Calders P, Praet M, Hoorens A, Geerts A, Verhelst X, Kaufman JM, Lapauw B. Bekaert M, et al. Among authors: ouwens dm. Obesity (Silver Spring). 2016 Dec;24(12):2544-2552. doi: 10.1002/oby.21674. Epub 2016 Oct 21. Obesity (Silver Spring). 2016. PMID: 27768254 Free article.
Combined gene and protein expression of hormone-sensitive lipase and adipose triglyceride lipase, mitochondrial content, and adipocyte size in subcutaneous and visceral adipose tissue of morbidly obese men.
De Naeyer H, Ouwens DM, Van Nieuwenhove Y, Pattyn P, 't Hart LM, Kaufman JM, Sell H, Eckel J, Cuvelier C, Taes YE, Ruige JB. De Naeyer H, et al. Among authors: ouwens dm. Obes Facts. 2011;4(5):407-16. doi: 10.1159/000333445. Epub 2011 Oct 14. Obes Facts. 2011. PMID: 22166762 Free PMC article.
Sex steroid-induced changes in circulating monocyte chemoattractant protein-1 levels may contribute to metabolic dysfunction in obese men.
Ruige JB, Bekaert M, Lapauw B, Fiers T, Lehr S, Hartwig S, Herzfeld de Wiza D, Schiller M, Passlack W, Van Nieuwenhove Y, Pattyn P, Cuvelier C, Taes YE, Sell H, Eckel J, Kaufman JM, Ouwens DM. Ruige JB, et al. Among authors: ouwens dm. J Clin Endocrinol Metab. 2012 Jul;97(7):E1187-91. doi: 10.1210/jc.2011-3069. Epub 2012 Apr 20. J Clin Endocrinol Metab. 2012. PMID: 22523336
113 results