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The cryptic IRF2BP2-RARA fusion transforms hematopoietic stem/progenitor cells and induces retinoid-sensitive acute promyelocytic leukemia.
Jovanovic JV, Chillón MC, Vincent-Fabert C, Dillon R, Voisset E, Gutiérrez NC, Sanz RG, Lopez AA, Morgan YG, Lok J, Solomon E, Duprez E, Díaz MG, Grimwade D. Jovanovic JV, et al. Among authors: solomon e. Leukemia. 2017 Mar;31(3):747-751. doi: 10.1038/leu.2016.338. Epub 2016 Nov 22. Leukemia. 2017. PMID: 27872498 No abstract available.
RARalpha-PLZF overcomes PLZF-mediated repression of CRABPI, contributing to retinoid resistance in t(11;17) acute promyelocytic leukemia.
Guidez F, Parks S, Wong H, Jovanovic JV, Mays A, Gilkes AF, Mills KI, Guillemin MC, Hobbs RM, Pandolfi PP, de Thé H, Solomon E, Grimwade D. Guidez F, et al. Among authors: solomon e. Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18694-9. doi: 10.1073/pnas.0704433104. Epub 2007 Nov 13. Proc Natl Acad Sci U S A. 2007. PMID: 18000064 Free PMC article.
Therapy-related leukaemias with balanced translocations can arise from pre-existing clonal haematopoiesis.
Dillon R, Ahearne MJ, Quek L, Potter N, Jovanovic J, Foot N, Valganon M, Jayne S, Dennis M, Raj K, Tauro S, Dyer MJS, Russell N, Solomon E, Grimwade D. Dillon R, et al. Among authors: solomon e. Leukemia. 2021 Aug;35(8):2407-2411. doi: 10.1038/s41375-021-01150-3. Epub 2021 Feb 5. Leukemia. 2021. PMID: 33547376 Free PMC article. No abstract available.
1,153 results