Zhang Y - Search Results

1

Allosteric Modulation: An Alternate Approach Targeting the Cannabinoid CB1 Receptor.

Nguyen T, Li JX, Thomas BF, Wiley JL, Kenakin TP, Zhang Y. Nguyen T, et al. Among authors: zhang y. Med Res Rev. 2017 May;37(3):441-474. doi: 10.1002/med.21418. Epub 2016 Nov 23. Med Res Rev. 2017. PMID: 27879006 Free PMC article. Review.

2

Synthesis and biological evaluation of bivalent ligands for the cannabinoid 1 receptor.

Zhang Y, Gilliam A, Maitra R, Damaj MI, Tajuba JM, Seltzman HH, Thomas BF. Zhang Y, et al. J Med Chem. 2010 Oct 14;53(19):7048-60. doi: 10.1021/jm1006676. J Med Chem. 2010. PMID: 20845959 Free PMC article.

3

Peripherally selective diphenyl purine antagonist of the CB1 receptor.

Fulp A, Bortoff K, Zhang Y, Snyder R, Fennell T, Marusich JA, Wiley JL, Seltzman H, Maitra R. Fulp A, et al. Among authors: zhang y. J Med Chem. 2013 Oct 24;56(20):8066-72. doi: 10.1021/jm401129n. Epub 2013 Sep 27. J Med Chem. 2013. PMID: 24041123 Free PMC article.

4

Toward the Development of Bivalent Ligand Probes of Cannabinoid CB1 and Orexin OX1 Receptor Heterodimers.

Perrey DA, Gilmour BP, Thomas BF, Zhang Y. Perrey DA, et al. Among authors: zhang y. ACS Med Chem Lett. 2014 Mar 25;5(6):634-8. doi: 10.1021/ml4004759. eCollection 2014 Jun 12. ACS Med Chem Lett. 2014. PMID: 24944734 Free PMC article.

5

Diarylureas as allosteric modulators of the cannabinoid CB1 receptor: structure-activity relationship studies on 1-(4-chlorophenyl)-3-{3-[6-(pyrrolidin-1-yl)pyridin-2-yl]phenyl}urea (PSNCBAM-1).

German N, Decker AM, Gilmour BP, Gay EA, Wiley JL, Thomas BF, Zhang Y. German N, et al. Among authors: zhang y. J Med Chem. 2014 Sep 25;57(18):7758-69. doi: 10.1021/jm501042u. Epub 2014 Sep 4. J Med Chem. 2014. PMID: 25162172 Free PMC article.

6

Effects of the cannabinoid CB₁ receptor allosteric modulator ORG 27569 on reinstatement of cocaine- and methamphetamine-seeking behavior in rats.

Jing L, Qiu Y, Zhang Y, Li JX. Jing L, et al. Among authors: zhang y. Drug Alcohol Depend. 2014 Oct 1;143:251-6. doi: 10.1016/j.drugalcdep.2014.08.004. Epub 2014 Aug 17. Drug Alcohol Depend. 2014. PMID: 25169627 Free PMC article.

7

Structure-activity relationships of substituted 1H-indole-2-carboxamides as CB1 receptor allosteric modulators.

Nguyen T, German N, Decker AM, Li JX, Wiley JL, Thomas BF, Kenakin TP, Zhang Y. Nguyen T, et al. Among authors: zhang y. Bioorg Med Chem. 2015 May 1;23(9):2195-2203. doi: 10.1016/j.bmc.2015.02.058. Epub 2015 Mar 7. Bioorg Med Chem. 2015. PMID: 25797163 Free PMC article.

8

The importance of the 6- and 7-positions of tetrahydroisoquinolines as selective antagonists for the orexin 1 receptor.

Perrey DA, Decker AM, Li JX, Gilmour BP, Thomas BF, Harris DL, Runyon SP, Zhang Y. Perrey DA, et al. Among authors: zhang y. Bioorg Med Chem. 2015 Sep 1;23(17):5709-24. doi: 10.1016/j.bmc.2015.07.013. Epub 2015 Jul 16. Bioorg Med Chem. 2015. PMID: 26216017 Free PMC article.

9

Novel Diarylurea Based Allosteric Modulators of the Cannabinoid CB1 Receptor: Evaluation of Importance of 6-Pyrrolidinylpyridinyl Substitution.

Nguyen T, German N, Decker AM, Langston TL, Gamage TF, Farquhar CE, Li JX, Wiley JL, Thomas BF, Zhang Y. Nguyen T, et al. Among authors: zhang y. J Med Chem. 2017 Sep 14;60(17):7410-7424. doi: 10.1021/acs.jmedchem.7b00707. Epub 2017 Aug 18. J Med Chem. 2017. PMID: 28792219 Free PMC article.

10

Diarylureas Containing 5-Membered Heterocycles as CB₁ Receptor Allosteric Modulators: Design, Synthesis, and Pharmacological Evaluation.

Nguyen T, Gamage TF, Decker AM, German N, Langston TL, Farquhar CE, Kenakin TP, Wiley JL, Thomas BF, Zhang Y. Nguyen T, et al. Among authors: zhang y. ACS Chem Neurosci. 2019 Jan 16;10(1):518-527. doi: 10.1021/acschemneuro.8b00396. Epub 2018 Sep 20. ACS Chem Neurosci. 2019. PMID: 30188693 Free PMC article.

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