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Tissue factor deficiency causes cardiac fibrosis and left ventricular dysfunction.
Pawlinski R, Fernandes A, Kehrle B, Pedersen B, Parry G, Erlich J, Pyo R, Gutstein D, Zhang J, Castellino F, Melis E, Carmeliet P, Baretton G, Luther T, Taubman M, Rosen E, Mackman N. Pawlinski R, et al. Among authors: mackman n. Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15333-8. doi: 10.1073/pnas.242501899. Epub 2002 Nov 8. Proc Natl Acad Sci U S A. 2002. PMID: 12426405 Free PMC article.
HIF-1alpha is essential for myeloid cell-mediated inflammation.
Cramer T, Yamanishi Y, Clausen BE, Förster I, Pawlinski R, Mackman N, Haase VH, Jaenisch R, Corr M, Nizet V, Firestein GS, Gerber HP, Ferrara N, Johnson RS. Cramer T, et al. Among authors: mackman n. Cell. 2003 Mar 7;112(5):645-57. doi: 10.1016/s0092-8674(03)00154-5. Cell. 2003. PMID: 12628185 Free PMC article.
PI3K-Akt pathway suppresses coagulation and inflammation in endotoxemic mice.
Schabbauer G, Tencati M, Pedersen B, Pawlinski R, Mackman N. Schabbauer G, et al. Among authors: mackman n. Arterioscler Thromb Vasc Biol. 2004 Oct;24(10):1963-9. doi: 10.1161/01.ATV.0000143096.15099.ce. Epub 2004 Aug 19. Arterioscler Thromb Vasc Biol. 2004. PMID: 15319270
529 results