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A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism.
Hefzi H, Ang KS, Hanscho M, Bordbar A, Ruckerbauer D, Lakshmanan M, Orellana CA, Baycin-Hizal D, Huang Y, Ley D, Martinez VS, Kyriakopoulos S, Jiménez NE, Zielinski DC, Quek LE, Wulff T, Arnsdorf J, Li S, Lee JS, Paglia G, Loira N, Spahn PN, Pedersen LE, Gutierrez JM, King ZA, Lund AM, Nagarajan H, Thomas A, Abdel-Haleem AM, Zanghellini J, Kildegaard HF, Voldborg BG, Gerdtzen ZP, Betenbaugh MJ, Palsson BO, Andersen MR, Nielsen LK, Borth N, Lee DY, Lewis NE. Hefzi H, et al. Among authors: li s. Cell Syst. 2016 Nov 23;3(5):434-443.e8. doi: 10.1016/j.cels.2016.10.020. Cell Syst. 2016. PMID: 27883890 Free PMC article.
Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion.
Gutierrez JM, Feizi A, Li S, Kallehauge TB, Hefzi H, Grav LM, Ley D, Baycin Hizal D, Betenbaugh MJ, Voldborg B, Faustrup Kildegaard H, Min Lee G, Palsson BO, Nielsen J, Lewis NE. Gutierrez JM, et al. Among authors: li s. Nat Commun. 2020 Jan 2;11(1):68. doi: 10.1038/s41467-019-13867-y. Nat Commun. 2020. PMID: 31896772 Free PMC article.
Recon 2.2: from reconstruction to model of human metabolism.
Swainston N, Smallbone K, Hefzi H, Dobson PD, Brewer J, Hanscho M, Zielinski DC, Ang KS, Gardiner NJ, Gutierrez JM, Kyriakopoulos S, Lakshmanan M, Li S, Liu JK, Martínez VS, Orellana CA, Quek LE, Thomas A, Zanghellini J, Borth N, Lee DY, Nielsen LK, Kell DB, Lewis NE, Mendes P. Swainston N, et al. Among authors: li s. Metabolomics. 2016;12:109. doi: 10.1007/s11306-016-1051-4. Epub 2016 Jun 7. Metabolomics. 2016. PMID: 27358602 Free PMC article.
A reference genome of the Chinese hamster based on a hybrid assembly strategy.
Rupp O, MacDonald ML, Li S, Dhiman H, Polson S, Griep S, Heffner K, Hernandez I, Brinkrolf K, Jadhav V, Samoudi M, Hao H, Kingham B, Goesmann A, Betenbaugh MJ, Lewis NE, Borth N, Lee KH. Rupp O, et al. Among authors: li s. Biotechnol Bioeng. 2018 Aug;115(8):2087-2100. doi: 10.1002/bit.26722. Epub 2018 May 29. Biotechnol Bioeng. 2018. PMID: 29704459 Free PMC article.
Reduced apoptosis in Chinese hamster ovary cells via optimized CRISPR interference.
Xiong K, Marquart KF, la Cour Karottki KJ, Li S, Shamie I, Lee JS, Gerling S, Yeo NC, Chavez A, Lee GM, Lewis NE, Kildegaard HF. Xiong K, et al. Among authors: li s. Biotechnol Bioeng. 2019 Jul;116(7):1813-1819. doi: 10.1002/bit.26969. Epub 2019 Apr 2. Biotechnol Bioeng. 2019. PMID: 30883679 Free PMC article.
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