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MAP3K11/GDF15 axis is a critical driver of cancer cachexia.
Lerner L, Tao J, Liu Q, Nicoletti R, Feng B, Krieger B, Mazsa E, Siddiquee Z, Wang R, Huang L, Shen L, Lin J, Vigano A, Chiu MI, Weng Z, Winston W, Weiler S, Gyuris J. Lerner L, et al. J Cachexia Sarcopenia Muscle. 2016 Sep;7(4):467-82. doi: 10.1002/jcsm.12077. Epub 2015 Oct 29. J Cachexia Sarcopenia Muscle. 2016. PMID: 27239403 Free PMC article.
Risk factors for lung cancer in COPD - results from the Bergen COPD cohort study.
Husebø GR, Nielsen R, Hardie J, Bakke PS, Lerner L, D'Alessandro-Gabazza C, Gyuris J, Gabazza E, Aukrust P, Eagan T. Husebø GR, et al. Among authors: lerner l. Respir Med. 2019 Jun;152:81-88. doi: 10.1016/j.rmed.2019.04.019. Epub 2019 Apr 30. Respir Med. 2019. PMID: 31128615 Free article.
ONCR-177, an Oncolytic HSV-1 Designed to Potently Activate Systemic Antitumor Immunity.
Haines BB, Denslow A, Grzesik P, Lee JS, Farkaly T, Hewett J, Wambua D, Kong L, Behera P, Jacques J, Goshert C, Ball M, Colthart A, Finer MH, Hayes MW, Feau S, Kennedy EM, Lerner L, Quéva C. Haines BB, et al. Among authors: lerner l. Cancer Immunol Res. 2021 Mar;9(3):291-308. doi: 10.1158/2326-6066.CIR-20-0609. Epub 2020 Dec 22. Cancer Immunol Res. 2021. PMID: 33355229
Compensatory insulin receptor (IR) activation on inhibition of insulin-like growth factor-1 receptor (IGF-1R): rationale for cotargeting IGF-1R and IR in cancer.
Buck E, Gokhale PC, Koujak S, Brown E, Eyzaguirre A, Tao N, Rosenfeld-Franklin M, Lerner L, Chiu MI, Wild R, Epstein D, Pachter JA, Miglarese MR. Buck E, et al. Among authors: lerner l. Mol Cancer Ther. 2010 Oct;9(10):2652-64. doi: 10.1158/1535-7163.MCT-10-0318. Epub 2010 Oct 5. Mol Cancer Ther. 2010. PMID: 20924128
Development of intravenously administered synthetic RNA virus immunotherapy for the treatment of cancer.
Kennedy EM, Denslow A, Hewett J, Kong L, De Almeida A, Bryant JD, Lee JS, Jacques J, Feau S, Hayes M, McMichael EL, Wambua D, Farkaly T, Rahmeh AA, Herschelman L, Douglas D, Spinale J, Adhikari S, Deterling J, Scott M, Haines BB, Finer MH, Ashburn TT, Quéva C, Lerner L. Kennedy EM, et al. Among authors: lerner l. Nat Commun. 2022 Oct 7;13(1):5907. doi: 10.1038/s41467-022-33599-w. Nat Commun. 2022. PMID: 36207308 Free PMC article.
312 results