Cole MD - Search Results

1

MYC Mediates mRNA Cap Methylation of Canonical Wnt/β-Catenin Signaling Transcripts By Recruiting CDK7 and RNA Methyltransferase.

Posternak V, Ung MH, Cheng C, Cole MD. Posternak V, et al. Among authors: cole md. Mol Cancer Res. 2017 Feb;15(2):213-224. doi: 10.1158/1541-7786.MCR-16-0247. Epub 2016 Nov 29. Mol Cancer Res. 2017. PMID: 27899423 Free PMC article.

2

Transcription Factor KLF5 Binds a Cyclin E1 Polymorphic Intronic Enhancer to Confer Increased Bladder Cancer Risk.

Pattison JM, Posternak V, Cole MD. Pattison JM, et al. Among authors: cole md. Mol Cancer Res. 2016 Nov;14(11):1078-1086. doi: 10.1158/1541-7786.MCR-16-0123. Epub 2016 Aug 11. Mol Cancer Res. 2016. PMID: 27514407 Free PMC article.

3

Strategically targeting MYC in cancer.

Posternak V, Cole MD. Posternak V, et al. Among authors: cole md. F1000Res. 2016 Mar 29;5:F1000 Faculty Rev-408. doi: 10.12688/f1000research.7879.1. eCollection 2016. F1000Res. 2016. PMID: 27081479 Free PMC article. Review.

4

MYC acts via the PTEN tumor suppressor to elicit autoregulation and genome-wide gene repression by activation of the Ezh2 methyltransferase.

Kaur M, Cole MD. Kaur M, et al. Among authors: cole md. Cancer Res. 2013 Jan 15;73(2):695-705. doi: 10.1158/0008-5472.CAN-12-2522. Epub 2012 Nov 7. Cancer Res. 2013. PMID: 23135913 Free PMC article.

5

Myc posttranscriptionally induces HIF1 protein and target gene expression in normal and cancer cells.

Doe MR, Ascano JM, Kaur M, Cole MD. Doe MR, et al. Among authors: cole md. Cancer Res. 2012 Feb 15;72(4):949-57. doi: 10.1158/0008-5472.CAN-11-2371. Epub 2011 Dec 20. Cancer Res. 2012. PMID: 22186139 Free PMC article.

6

Specific regulation of mRNA cap methylation by the c-Myc and E2F1 transcription factors.

Cole MD, Cowling VH. Cole MD, et al. Oncogene. 2009 Mar 5;28(9):1169-75. doi: 10.1038/onc.2008.463. Epub 2009 Jan 12. Oncogene. 2009. PMID: 19137018 Free PMC article.

7

HATs off to capping: a new mechanism for Myc.

Cowling VH, Cole MD. Cowling VH, et al. Among authors: cole md. Cell Cycle. 2007 Apr 15;6(8):907-9. doi: 10.4161/cc.6.8.4123. Epub 2007 Apr 8. Cell Cycle. 2007. PMID: 17404507

8

Turning the tables: Myc activates Wnt in breast cancer.

Cowling VH, Cole MD. Cowling VH, et al. Among authors: cole md. Cell Cycle. 2007 Nov 1;6(21):2625-7. doi: 10.4161/cc.6.21.4880. Epub 2007 Aug 13. Cell Cycle. 2007. PMID: 17726380 Review.

9

The Myc transactivation domain promotes global phosphorylation of the RNA polymerase II carboxy-terminal domain independently of direct DNA binding.

Cowling VH, Cole MD. Cowling VH, et al. Among authors: cole md. Mol Cell Biol. 2007 Mar;27(6):2059-73. doi: 10.1128/MCB.01828-06. Epub 2007 Jan 22. Mol Cell Biol. 2007. PMID: 17242204 Free PMC article.

10

Transcription-independent functions of MYC: regulation of translation and DNA replication.

Cole MD, Cowling VH. Cole MD, et al. Nat Rev Mol Cell Biol. 2008 Oct;9(10):810-5. doi: 10.1038/nrm2467. Epub 2008 Aug 13. Nat Rev Mol Cell Biol. 2008. PMID: 18698328 Free PMC article. Review.

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