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Sensitive liquid chromatography mass spectrometry (LC-MS) assay reveals novel insights on DNA methylation and incorporation of gemcitabine, its metabolite difluorodeoxyuridine, deoxyuridine, and RX-3117 into DNA.
Honeywell RJ, Sarkisjan D, Kathmann I, Kristensen MH, Peters GJ. Honeywell RJ, et al. Among authors: sarkisjan d. Nucleosides Nucleotides Nucleic Acids. 2016 Dec;35(10-12):652-662. doi: 10.1080/15257770.2016.1216566. Nucleosides Nucleotides Nucleic Acids. 2016. PMID: 27906622
RX-3117 (fluorocyclopentenyl cytosine): a novel specific antimetabolite for selective cancer treatment.
Balboni B, El Hassouni B, Honeywell RJ, Sarkisjan D, Giovannetti E, Poore J, Heaton C, Peterson C, Benaim E, Lee YB, Kim DJ, Peters GJ. Balboni B, et al. Among authors: sarkisjan d. Expert Opin Investig Drugs. 2019 Apr;28(4):311-322. doi: 10.1080/13543784.2019.1583742. Epub 2019 Mar 16. Expert Opin Investig Drugs. 2019. PMID: 30879349 Free article. Review.
Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment.
Dirkse A, Golebiewska A, Buder T, Nazarov PV, Muller A, Poovathingal S, Brons NHC, Leite S, Sauvageot N, Sarkisjan D, Seyfrid M, Fritah S, Stieber D, Michelucci A, Hertel F, Herold-Mende C, Azuaje F, Skupin A, Bjerkvig R, Deutsch A, Voss-Böhme A, Niclou SP. Dirkse A, et al. Among authors: sarkisjan d. Nat Commun. 2019 Apr 16;10(1):1787. doi: 10.1038/s41467-019-09853-z. Nat Commun. 2019. PMID: 30992437 Free PMC article.