Orzeszko A - Search Results

1

Benzimidazole inhibitors of protein kinase CK2 potently inhibit the activity of atypical protein kinase Rio1.

Kubiński K, Masłyk M, Orzeszko A. Kubiński K, et al. Among authors: orzeszko a. Mol Cell Biochem. 2017 Feb;426(1-2):195-203. doi: 10.1007/s11010-016-2892-x. Epub 2016 Dec 1. Mol Cell Biochem. 2017. PMID: 27909846 Free PMC article.

2

Synthesis of new analogs of benzotriazole, benzimidazole and phthalimide--potential inhibitors of human protein kinase CK2.

Najda-Bernatowicz A, Łebska M, Orzeszko A, Kopańska K, Krzywińska E, Muszyńska G, Bretner M. Najda-Bernatowicz A, et al. Among authors: orzeszko a. Bioorg Med Chem. 2009 Feb 15;17(4):1573-8. doi: 10.1016/j.bmc.2008.12.071. Epub 2009 Jan 7. Bioorg Med Chem. 2009. PMID: 19168362

3

Tetraiodobenzimidazoles are potent inhibitors of protein kinase CK2.

Gianoncelli A, Cozza G, Orzeszko A, Meggio F, Kazimierczuk Z, Pinna LA. Gianoncelli A, et al. Among authors: orzeszko a. Bioorg Med Chem. 2009 Oct 15;17(20):7281-9. doi: 10.1016/j.bmc.2009.08.047. Epub 2009 Aug 27. Bioorg Med Chem. 2009. PMID: 19748274

4

ATP site-directed inhibitors of protein kinase CK2: an update.

Sarno S, Papinutto E, Franchin C, Bain J, Elliott M, Meggio F, Kazimierczuk Z, Orzeszko A, Zanotti G, Battistutta R, Pinna LA. Sarno S, et al. Among authors: orzeszko a. Curr Top Med Chem. 2011;11(11):1340-51. doi: 10.2174/156802611795589638. Curr Top Med Chem. 2011. PMID: 21513497 Review.

5

CK2α and CK2α' subunits differ in their sensitivity to 4,5,6,7-tetrabromo- and 4,5,6,7-tetraiodo-1H-benzimidazole derivatives.

Janeczko M, Orzeszko A, Kazimierczuk Z, Szyszka R, Baier A. Janeczko M, et al. Among authors: orzeszko a. Eur J Med Chem. 2012 Jan;47(1):345-50. doi: 10.1016/j.ejmech.2011.11.002. Epub 2011 Nov 13. Eur J Med Chem. 2012. PMID: 22115617

6

Cell-permeable dual inhibitors of protein kinases CK2 and PIM-1: structural features and pharmacological potential.

Cozza G, Girardi C, Ranchio A, Lolli G, Sarno S, Orzeszko A, Kazimierczuk Z, Battistutta R, Ruzzene M, Pinna LA. Cozza G, et al. Among authors: orzeszko a. Cell Mol Life Sci. 2014 Aug;71(16):3173-85. doi: 10.1007/s00018-013-1552-5. Epub 2014 Jan 18. Cell Mol Life Sci. 2014. PMID: 24442476 Free PMC article.

7

In Search of the Antimicrobial Potential of Benzimidazole Derivatives.

Janeczko M, Kazimierczuk Z, Orzeszko A, Niewiadomy A, Król E, Szyszka R, Masłyk M. Janeczko M, et al. Among authors: orzeszko a. Pol J Microbiol. 2016 Aug 26;65(3):359-364. doi: 10.5604/17331331.1215615. Pol J Microbiol. 2016. PMID: 29334067 Free article.

8

Antitumor activity of the protein kinase inhibitor 1-(β-D-2'-deoxyribofuranosyl)-4,5,6,7-tetrabromo- 1H-benzimidazole in breast cancer cell lines.

Koronkiewicz M, Kazimierczuk Z, Orzeszko A. Koronkiewicz M, et al. Among authors: orzeszko a. BMC Cancer. 2022 Oct 15;22(1):1069. doi: 10.1186/s12885-022-10156-8. BMC Cancer. 2022. PMID: 36243702 Free PMC article.

9

The selectivity of inhibitors of protein kinase CK2: an update.

Pagano MA, Bain J, Kazimierczuk Z, Sarno S, Ruzzene M, Di Maira G, Elliott M, Orzeszko A, Cozza G, Meggio F, Pinna LA. Pagano MA, et al. Among authors: orzeszko a. Biochem J. 2008 Nov 1;415(3):353-65. doi: 10.1042/BJ20080309. Biochem J. 2008. PMID: 18588507

10

Structural study of selected polyhalogenated benzimidazoles (protein kinase CK2 inhibitors) by nuclear quadrupole double resonance, X-ray, and density functional theory.

Latosińska JN, Latosińska M, Seliger J, Zagar V, Maurin JK, Orzeszko A, Kazimierczuk Z. Latosińska JN, et al. Among authors: orzeszko a. J Phys Chem A. 2010 Jan 14;114(1):563-75. doi: 10.1021/jp9075492. J Phys Chem A. 2010. PMID: 20055520

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