Xie Q - Search Results

1

Discovery, synthesis, biological evaluation and structure-based optimization of novel piperidine derivatives as acetylcholine-binding protein ligands.

Shen J, Yang XC, Yu MC, Xiao L, Zhang XJ, Sun HJ, Chen H, Pan GX, Yan YR, Wang SC, Li W, Zhou L, Xie Q, Yu LQ, Wang YH, Shao LM. Shen J, et al. Among authors: xie q. Acta Pharmacol Sin. 2017 Jan;38(1):146-155. doi: 10.1038/aps.2016.124. Epub 2016 Dec 5. Acta Pharmacol Sin. 2017. PMID: 27917874 Free PMC article.

2

Investigation of the binding mode of (-)-meptazinol and bis-meptazinol derivatives on acetylcholinesterase using a molecular docking method.

Xie Q, Tang Y, Li W, Wang XH, Qiu ZB. Xie Q, et al. J Mol Model. 2006 Mar;12(4):390-7. doi: 10.1007/s00894-005-0058-y. Epub 2006 Jan 11. J Mol Model. 2006. PMID: 16404617

3

3D-QSAR studies of orvinol analogs as kappa-opioid agonists.

Li W, Tang Y, Xie Q, Sheng W, Qiu ZB. Li W, et al. Among authors: xie q. J Mol Model. 2006 Sep;12(6):877-84. doi: 10.1007/s00894-005-0084-9. Epub 2006 Mar 22. J Mol Model. 2006. PMID: 16552460

4

Conformational re-analysis of (+)-meptazinol: an opioid with mixed analgesic pharmacophores.

Li W, Wang XH, Lau CW, Tang Y, Xie Q, Qiu ZB. Li W, et al. Among authors: xie q. Acta Pharmacol Sin. 2006 Sep;27(9):1247-52. doi: 10.1111/j.1745-7254.2006.00375.x. Acta Pharmacol Sin. 2006. PMID: 16923347

5

Bis-(-)-nor-meptazinols as novel nanomolar cholinesterase inhibitors with high inhibitory potency on amyloid-beta aggregation.

Xie Q, Wang H, Xia Z, Lu M, Zhang W, Wang X, Fu W, Tang Y, Sheng W, Li W, Zhou W, Zhu X, Qiu Z, Chen H. Xie Q, et al. J Med Chem. 2008 Apr 10;51(7):2027-36. doi: 10.1021/jm070154q. Epub 2008 Mar 12. J Med Chem. 2008. PMID: 18333606

6

Highly selective and potent mu opioid ligands by unexpected substituent on morphine skeleton.

Li W, Tao YM, Tang Y, Xu XJ, Chen J, Fu W, Wang XH, Chao B, Sheng W, Xie Q, Qiu ZB, Liu JG. Li W, et al. Among authors: xie q. Bioorg Med Chem Lett. 2010 Jan 1;20(1):418-21. doi: 10.1016/j.bmcl.2009.07.119. Epub 2009 Jul 29. Bioorg Med Chem Lett. 2010. PMID: 19932964

7

Novel bis-(-)-nor-meptazinol derivatives act as dual binding site AChE inhibitors with metal-complexing property.

Zheng W, Li J, Qiu Z, Xia Z, Li W, Yu L, Chen H, Chen J, Chen Y, Hu Z, Zhou W, Shao B, Cui Y, Xie Q, Chen H. Zheng W, et al. Among authors: xie q. Toxicol Appl Pharmacol. 2012 Oct 1;264(1):65-72. doi: 10.1016/j.taap.2012.07.018. Epub 2012 Jul 25. Toxicol Appl Pharmacol. 2012. PMID: 22842334

8

Triple reuptake inhibitors: a patent review (2006 - 2012).

Shao L, Li W, Xie Q, Yin H. Shao L, et al. Among authors: xie q. Expert Opin Ther Pat. 2014 Feb;24(2):131-54. doi: 10.1517/13543776.2014.859676. Epub 2013 Nov 30. Expert Opin Ther Pat. 2014. PMID: 24289044 Review.

9

Microwave-Assisted Synthesis of Phenanthridines by Radical Insertion/Cyclization of Biphenyl Isocyanides.

Xu Y, Chen Y, Li W, Xie Q, Shao L. Xu Y, et al. Among authors: xie q. J Org Chem. 2016 Sep 16;81(18):8426-35. doi: 10.1021/acs.joc.6b01589. Epub 2016 Aug 26. J Org Chem. 2016. PMID: 27529185

10

The Pharmacological Heterogeneity of Nepenthone Analogs in Conferring Highly Selective and Potent κ-Opioid Agonistic Activities.

Li W, Long JD, Qian YY, Long Y, Xu XJ, Wang YJ, Shen Q, Wang ZN, Yang XC, Xiao L, Sun HP, Xu YL, Chen YY, Xie Q, Wang YH, Shao LM, Liu JG, Qiu ZB, Fu W. Li W, et al. Among authors: xie q. ACS Chem Neurosci. 2017 Apr 19;8(4):766-776. doi: 10.1021/acschemneuro.6b00321. Epub 2017 Jan 19. ACS Chem Neurosci. 2017. PMID: 28033462

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