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Structure-Activity Relationship, Drug Metabolism and Pharmacokinetics Properties Optimization, and in Vivo Studies of New Brain Penetrant Triple T-Type Calcium Channel Blockers.
Siegrist R, Pozzi D, Jacob G, Torrisi C, Colas K, Braibant B, Mawet J, Pfeifer T, de Kanter R, Roch C, Kessler M, Moon R, Corminboeuf O, Bezençon O. Siegrist R, et al. Among authors: moon r. J Med Chem. 2016 Dec 8;59(23):10661-10675. doi: 10.1021/acs.jmedchem.6b01356. Epub 2016 Nov 23. J Med Chem. 2016. PMID: 27933950
Correction to Structure-Activity Relationship, Drug Metabolism and Pharmacokinetics Properties Optimization, and in Vivo Studies of New Brain Penetrant Triple T-Type Calcium Channel Blockers.
Siegrist R, Pozzi D, Jacob G, Torrisi C, Colas K, Braibant B, Mawet J, Pfeifer T, de Kanter R, Roch C, Kessler M, Moon R, Corminboeuf O, Bezençon O. Siegrist R, et al. Among authors: moon r. J Med Chem. 2017 Mar 9;60(5):2163. doi: 10.1021/acs.jmedchem.7b00219. Epub 2017 Feb 24. J Med Chem. 2017. PMID: 28234473 No abstract available.
Discovery and evaluation of Cav3.1-selective T-type calcium channel blockers.
Bezençon O, Remeň L, Richard S, Roch C, Kessler M, Moon R, Mawet J, Ertel EA, Pfeifer T, Capeleto B. Bezençon O, et al. Among authors: moon r. Bioorg Med Chem Lett. 2017 Dec 1;27(23):5322-5325. doi: 10.1016/j.bmcl.2017.09.063. Epub 2017 Oct 3. Bioorg Med Chem Lett. 2017. PMID: 29066309
Milestones to the Discovery of T-type Calcium Channel Blockers for the Treatment of Generalized Epilepsies.
Bezençon O, Siegrist R, Heidmann B, Pozzi D, Stamm S, Remeň L, Richard S, Simons L, Gaston R, Downing D, Grisostomi C, Roch C, Kessler M, Gatfield J, Moon R, Pfeifer T, Mosbacher J, Reymond I, Ertel EA, de Kanter R, Capeleto B, Fournier E, Rey M, Moccia L, Toeroek-Schafroth M, Roscher R, Schindelholz B. Bezençon O, et al. Among authors: moon r. Chimia (Aarau). 2017 Oct 25;71(10):722-729. doi: 10.2533/chimia.2017.722. Chimia (Aarau). 2017. PMID: 29070417 Free article.
Discovery and evaluation of Cav3.2-selective T-type calcium channel blockers.
Bezençon O, Remeň L, Richard S, Roch C, Kessler M, Ertel EA, Moon R, Mawet J, Pfeifer T, Capeleto B. Bezençon O, et al. Among authors: moon r. Bioorg Med Chem Lett. 2017 Dec 1;27(23):5326-5331. doi: 10.1016/j.bmcl.2017.09.062. Epub 2017 Sep 30. Bioorg Med Chem Lett. 2017. PMID: 29074257
Discovery of a Potent, Selective T-type Calcium Channel Blocker as a Drug Candidate for the Treatment of Generalized Epilepsies.
Bezençon O, Heidmann B, Siegrist R, Stamm S, Richard S, Pozzi D, Corminboeuf O, Roch C, Kessler M, Ertel EA, Reymond I, Pfeifer T, de Kanter R, Toeroek-Schafroth M, Moccia LG, Mawet J, Moon R, Rey M, Capeleto B, Fournier E. Bezençon O, et al. Among authors: moon r. J Med Chem. 2017 Dec 14;60(23):9769-9789. doi: 10.1021/acs.jmedchem.7b01236. Epub 2017 Nov 20. J Med Chem. 2017. PMID: 29116786
Genome sequencing of Plasmodium malariae identifies continental segregation and mutations associated with reduced pyrimethamine susceptibility.
Ibrahim A, Mohring F, Manko E, van Schalkwyk DA, Phelan JE, Nolder D, Borrmann S, Adegnika AA, Di Santi SM, Alam MS, Mondal D, Nosten F, Sutherland CJ, Moon RW, Clark TG, Campino S. Ibrahim A, et al. Among authors: moon rw. Nat Commun. 2024 Dec 30;15(1):10779. doi: 10.1038/s41467-024-55102-3. Nat Commun. 2024. PMID: 39738025 Free PMC article.
Elevation of spectral components of electrodermal activity precedes central nervous system oxygen toxicity symptoms in divers.
Posada-Quintero HF, Derrick BJ, Ellis MC, Natoli MJ, Winstead-Derlega C, Gonzalez SI, Allen CM, Makowski MS, Keuski BM, Moon RE, Freiberger JJ, Chon KH. Posada-Quintero HF, et al. Among authors: moon re. Commun Med (Lond). 2024 Dec 19;4(1):270. doi: 10.1038/s43856-024-00688-4. Commun Med (Lond). 2024. PMID: 39702758 Free PMC article.
1,277 results