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Ursodeoxycholic acid exerts farnesoid X receptor-antagonistic effects on bile acid and lipid metabolism in morbid obesity.
Mueller M, Thorell A, Claudel T, Jha P, Koefeler H, Lackner C, Hoesel B, Fauler G, Stojakovic T, Einarsson C, Marschall HU, Trauner M. Mueller M, et al. Among authors: marschall hu. J Hepatol. 2015 Jun;62(6):1398-404. doi: 10.1016/j.jhep.2014.12.034. Epub 2015 Jan 21. J Hepatol. 2015. PMID: 25617503 Free PMC article. Clinical Trial.
Inhibition of intestinal bile acid absorption improves cholestatic liver and bile duct injury in a mouse model of sclerosing cholangitis.
Baghdasaryan A, Fuchs CD, Österreicher CH, Lemberger UJ, Halilbasic E, Påhlman I, Graffner H, Krones E, Fickert P, Wahlström A, Ståhlman M, Paumgartner G, Marschall HU, Trauner M. Baghdasaryan A, et al. Among authors: marschall hu. J Hepatol. 2016 Mar;64(3):674-81. doi: 10.1016/j.jhep.2015.10.024. Epub 2015 Oct 31. J Hepatol. 2016. PMID: 26529078 Free article.
STK25 is a critical determinant in nonalcoholic steatohepatitis.
Amrutkar M, Chursa U, Kern M, Nuñez-Durán E, Ståhlman M, Sütt S, Borén J, Johansson BR, Marschall HU, Blüher M, Mahlapuu M. Amrutkar M, et al. Among authors: marschall hu. FASEB J. 2016 Oct;30(10):3628-3643. doi: 10.1096/fj.201600562R. Epub 2016 Jul 15. FASEB J. 2016. PMID: 27421788
NorUrsodeoxycholic acid ameliorates cholemic nephropathy in bile duct ligated mice.
Krones E, Eller K, Pollheimer MJ, Racedo S, Kirsch AH, Frauscher B, Wahlström A, Ståhlman M, Trauner M, Grahammer F, Huber TB, Wagner K, Rosenkranz AR, Marschall HU, Fickert P. Krones E, et al. Among authors: marschall hu. J Hepatol. 2017 Jul;67(1):110-119. doi: 10.1016/j.jhep.2017.02.019. Epub 2017 Feb 27. J Hepatol. 2017. PMID: 28242240
254 results