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Argininosuccinate Synthetase 1 Loss in Invasive Bladder Cancer Regulates Survival through General Control Nonderepressible 2 Kinase-Mediated Eukaryotic Initiation Factor 2α Activity and Is Targetable by Pegylated Arginine Deiminase.
Sahu D, Gupta S, Hau AM, Nakashima K, Leivo MZ, Searles SC, Elson P, Bomalaski JS, Casteel DE, Boss GR, Hansel DE. Sahu D, et al. Among authors: searles sc. Am J Pathol. 2017 Jan;187(1):200-213. doi: 10.1016/j.ajpath.2016.09.004. Epub 2016 Dec 9. Am J Pathol. 2017. PMID: 27979310 Free PMC article.
Nrf2 Induces IL-17D to Mediate Tumor and Virus Surveillance.
Saddawi-Konefka R, Seelige R, Gross ET, Levy E, Searles SC, Washington A Jr, Santosa EK, Liu B, O'Sullivan TE, Harismendy O, Bui JD. Saddawi-Konefka R, et al. Among authors: searles sc. Cell Rep. 2016 Aug 30;16(9):2348-58. doi: 10.1016/j.celrep.2016.07.075. Epub 2016 Aug 18. Cell Rep. 2016. PMID: 27545889 Free PMC article.
Cell-cell fusion as a mechanism of DNA exchange in cancer.
Searles SC, Santosa EK, Bui JD. Searles SC, et al. Oncotarget. 2017 Dec 27;9(5):6156-6173. doi: 10.18632/oncotarget.23715. eCollection 2018 Jan 19. Oncotarget. 2017. PMID: 29464062 Free PMC article.
IRE1α regulates macrophage polarization, PD-L1 expression, and tumor survival.
Batista A, Rodvold JJ, Xian S, Searles SC, Lew A, Iwawaki T, Almanza G, Waller TC, Lin J, Jepsen K, Carter H, Zanetti M. Batista A, et al. Among authors: searles sc. PLoS Biol. 2020 Jun 10;18(6):e3000687. doi: 10.1371/journal.pbio.3000687. eCollection 2020 Jun. PLoS Biol. 2020. PMID: 32520957 Free PMC article.
Innate sensing of cancer's non-immunologic hallmarks.
Seelige R, Searles S, Bui JD. Seelige R, et al. Curr Opin Immunol. 2018 Feb;50:1-8. doi: 10.1016/j.coi.2017.09.005. Epub 2017 Oct 12. Curr Opin Immunol. 2018. PMID: 29032295 Free PMC article. Review.
19 results